Cholesterol Chloroformate
Names
[ CAS No. ]:
7144-08-3
[ Name ]:
Cholesterol Chloroformate
[Synonym ]:
Cholesteryloxycarbonyl chloride
Carbonochloridic acid, (3β)-cholest-5-en-3-yl ester
Cholesterol Chloroformate
Cholesterol, chloroformate (8CI)
[(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] carbonochloridate
Cholesterol, chloroformate
Cholesteryl chloroformate
MFCD00003633
EINECS 230-447-9
(3β)-Cholest-5-en-3-yl carbonochloridate
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
504.0±20.0 °C at 760 mmHg
[ Melting Point ]:
115-117 °C(lit.)
[ Molecular Formula ]:
C28H45ClO2
[ Molecular Weight ]:
449.109
[ Flash Point ]:
203.1±15.2 °C
[ Exact Mass ]:
448.310822
[ PSA ]:
26.30000
[ LogP ]:
11.50
[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C
[ Index of Refraction ]:
1.524
[ Water Solubility ]:
SLOWLY HYDROLYZED
MSDS
Safety Information
[ Symbol ]:
GHS05
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H314
[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
[ Hazard Codes ]:
C:Corrosive;
[ Risk Phrases ]:
R34
[ Safety Phrases ]:
S26-S36/37/39-S45
[ RIDADR ]:
UN 3261 8/PG 2
[ WGK Germany ]:
3
[ Packaging Group ]:
II
[ Hazard Class ]:
8
[ HS Code ]:
29159020
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 29159020
Articles
Eur. J. Pharm. Sci. 59 , 83-93, (2014)
Gene transfer using non-viral vectors is a promising approach for the safe delivery of nucleic acid therapeutics. In this study, we investigate a lipid-based system for targeted gene delivery to malig...
Balancing polymer hydrophobicity for ligand presentation and siRNA delivery in dual function CXCR4 inhibiting polyplexes.Biomater. Sci. 3 , 1114-23, (2015)
In the present study, a series of copolymers (PAMD-Ch) was synthesized by grafting polymeric Plerixafor/AMD3100 (PAMD) with different amounts of cholesterol and the effect of cholesterol modification ...
Cholesterol anchored arabinogalactan for asialoglycoprotein receptor targeting: synthesis, characterization, and proof of concept of hepatospecific delivery.Carbohydr. Res. 408 , 33-43, (2015)
Asialoglycoprotein receptors (ASGPR) are hepatocyte bound receptors, which exhibit receptor mediated endocytosis (RME) for galactose specific moieties. Arabinogalactan (AG), a liver specific high gala...