Methanesulfonic acid
Names
[ CAS No. ]:
75-75-2
[ Name ]:
Methanesulfonic acid
[Synonym ]:
EINECS 200-898-6
Mesic acid
MFCD00007518
methane sulfonic acid
Methanesulfonic acid
Methanesulphonic acid
CH3SO3H
Methylsulfonic acid
Methane sulfonicacid
Chemical & Physical Properties
[ Density]:
1.5±0.1 g/cm3
[ Boiling Point ]:
167 °C10 mm Hg(lit.)
[ Melting Point ]:
19 °C
[ Molecular Formula ]:
CH4O3S
[ Molecular Weight ]:
96.106
[ Flash Point ]:
>230 °F
[ Exact Mass ]:
95.988113
[ PSA ]:
62.75000
[ LogP ]:
-1.89
[ Vapour density ]:
3.3 (vs air)
[ Vapour Pressure ]:
1 mm Hg ( 20 °C)
[ Index of Refraction ]:
1.448
[ Stability ]:
Stable. Moisture sensitive. Incompatible with amines, bases, water, common metals. Releases a substantial amount of heat when diluted with water (add acid to water with care if diluting).
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- PB1140000
- CHEMICAL NAME :
- Methanesulfonic acid
- CAS REGISTRY NUMBER :
- 75-75-2
- BEILSTEIN REFERENCE NO. :
- 1446024
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 11
- MOLECULAR FORMULA :
- C-H4-O3-S
- MOLECULAR WEIGHT :
- 96.11
- WISWESSER LINE NOTATION :
- WSQ1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- KODAK* Kodak Company Reports. (343 State St., Rochester, NY 14650) Volume(issue)/page/year: 21MAY1971
- TYPE OF TEST :
- LC - Lethal concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >330 ppm/6H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- KODAK* Kodak Company Reports. (343 State St., Rochester, NY 14650) Volume(issue)/page/year: 21MAY1971
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- >2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- KODAK* Kodak Company Reports. (343 State St., Rochester, NY 14650) Volume(issue)/page/year: 21MAY1971
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - quail
- DOSE/DURATION :
- 1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960- Volume(issue)/page/year: 48,371,1976 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83577 No. of Facilities: 82 (estimated) No. of Industries: 3 No. of Occupations: 9 No. of Employees: 1209 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83577 No. of Facilities: 325 (estimated) No. of Industries: 7 No. of Occupations: 13 No. of Employees: 8084 (estimated) No. of Female Employees: 1393 (estimated)
Safety Information
[ Symbol ]:
GHS05, GHS07
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H290-H302 + H312-H314-H335
[ Precautionary Statements ]:
P301 + P312 + P330-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338
[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
C:Corrosive
[ Risk Phrases ]:
R34
[ Safety Phrases ]:
S26-S36-S45-S1/2-S36/37/39
[ RIDADR ]:
UN 3265 8/PG 2
[ WGK Germany ]:
1
[ RTECS ]:
PB1140000
[ Packaging Group ]:
III
[ Hazard Class ]:
8
[ HS Code ]:
2904100000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2904100000
[ Summary ]:
2904100000 derivatives containing only sulpho groups, their salts and ethyl esters。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%
Articles
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Corticosteroid and endocannabinoid actions converge on prefrontocortical circuits associated with neuropsychiatric illnesses. Corticosteroids can also modulate forebrain synapses by using endocannabin...
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Sterol response element binding protein (SREBP) is a key transcription factor in insulin and glucose metabolism. We previously demonstrated that elevated levels of membrane sphingomyelin (SM) were rel...