2-Methylcyclopentane-1,3-dione

Names

[ CAS No. ]:
765-69-5

[ Name ]:
2-Methylcyclopentane-1,3-dione

[Synonym ]:
1,3-Cyclopentanedione, 2-methyl-
2-methyl-1,3-cyclo-pentanedione
2-Methylcyclopentan-1,3-dion
Cyclopentanecarbonylchloride,2-methyl
MFCD00001406
2-methylcyclopentane-1,3-dione
2-Methyl-1,3-cyclopentanedione
2-methylcyclopentanecarbonyl chloride
2-methyl-cyclopentane-1,3-dione
2-methyl-cyclopentan-1,3-dione
EINECS 212-153-2
2-Methyl-1,3-cyclopentadione
2-Methyl-cyclopentan-1-carbonsaeure-chlorid

Biological Activity

[Description]:

2-Methylcyclopentane-1,3-dione is a key intermediate for the total synthesis of steroids[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Victor J. Grenda, et al. A convenient synthesis of 2-methylcyclopentane-1,3-dione. RETURN TO ISSUEPREVARTICLENEXT

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
218.0±23.0 °C at 760 mmHg

[ Melting Point ]:
212-215 °C(lit.)

[ Molecular Formula ]:
C₆H₈O₂

[ Molecular Weight ]:
112.127

[ Flash Point ]:
78.5±19.6 °C

[ Exact Mass ]:
112.052429

[ PSA ]:
34.14000

[ LogP ]:
-0.78

[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.463

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
29142900

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2914299000

[ Summary ]:
2914299000. other cyclanic, cyclenic or cyclotherpenic ketones without other oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

Articles

Identification and characterization of novel benzil (diphenylethane-1,2-dione) analogues as inhibitors of mammalian carboxylesterases.

J. Med. Chem. 48 , 2906-15, (2005)

Carboxylesterases (CE) are ubiquitous enzymes responsible for the metabolism of xenobiotics. Because the structural and amino acid homology among esterases of different classes, the identification of ...

Enantiomeric deoxycholic acid: total synthesis, characterization, and preliminary toxicity toward colon cancer cell lines.

J. Org. Chem. 72(24) , 9298-307, (2007)

Deoxycholic acid (DCA) is an endogenous secondary bile acid implicated in numerous pathological conditions including colon cancer formation and progression and cholestatic liver disease. DCA involveme...

Dyotropic rearrangements of fused tricyclic β-lactones: application to the synthesis of (-)-curcumanolide A and (-)-curcumalactone.

J. Am. Chem. Soc. 134(32) , 13348-56, (2012)

Dyotropic rearrangements of fused, tricyclic β-lactones are described that proceed via unprecedented stereospecific, 1,2-acyl migrations delivering bridged, spiro-γ-butyrolactones. A unique example of...

Related Compounds

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