2,3,4,5,6-Pentafluoroaniline
Names
[ CAS No. ]:
771-60-8
[ Name ]:
2,3,4,5,6-Pentafluoroaniline
[Synonym ]:
Aniline,2,3,4,5,6-pentafluoro
2H-tetrafluoroacetanilide
EINECS 212-234-2
Pentafluorophenylamine
Pentafluoroaniline
Aminopentafluorobenzene
2,3',4,4',5-PENTACHLOROBIPHENYL ETHER
perfluoroaniline
Benzenamine,2,3,4,5,6-pentafluoro
MFCD00007643
2,3,4,5,6-pentafluorophenylamine
2,3,4,5,6-pentafluoroanilline
Benzenamine, 2,3,4,5,6-pentafluoro-
2,3,4,5,6-Pentafluorobenzenamine
Chemical & Physical Properties
[ Density]:
1.6±0.1 g/cm3
[ Boiling Point ]:
156.4±35.0 °C at 760 mmHg
[ Melting Point ]:
33-35 °C(lit.)
[ Molecular Formula ]:
C6H2F5N
[ Molecular Weight ]:
183.079
[ Flash Point ]:
73.9±0.0 °C
[ Exact Mass ]:
183.010742
[ PSA ]:
26.02000
[ LogP ]:
2.65
[ Vapour Pressure ]:
2.9±0.3 mmHg at 25°C
[ Index of Refraction ]:
1.453
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- BY7920000
- CHEMICAL NAME :
- Aniline, 2,3,4,5,6-pentafluoro-
- CAS REGISTRY NUMBER :
- 771-60-8
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C6-H2-F5-N
- MOLECULAR WEIGHT :
- 183.09
- WISWESSER LINE NOTATION :
- ZR BF CF DF EF FF
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 390 mg/kg
- TOXIC EFFECTS :
- Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - respiratory depression Nutritional and Gross Metabolic - body temperature decrease
- REFERENCE :
- IZSBAI Izvestiya Sibirskogo Otdeleniya Akademii Nauk SSSR, Seriya Biologomeditsinskikh Nauk. (Novosibirsk, USSR) No.1-3, 1963-68. For publisher information, see ISBNBN. Volume(issue)/page/year: 3,91,1965
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 384 mg/kg
- TOXIC EFFECTS :
- Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - respiratory depression Nutritional and Gross Metabolic - body temperature decrease
- REFERENCE :
- IZSBAI Izvestiya Sibirskogo Otdeleniya Akademii Nauk SSSR, Seriya Biologomeditsinskikh Nauk. (Novosibirsk, USSR) No.1-3, 1963-68. For publisher information, see ISBNBN. Volume(issue)/page/year: 3,91,1965
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn:Harmful;
[ Risk Phrases ]:
R22;R36/37/38
[ Safety Phrases ]:
S26-S36-S36/37/39
[ RIDADR ]:
2811.0
[ WGK Germany ]:
3
[ RTECS ]:
BY7920000
[ Packaging Group ]:
I; II; III
[ Hazard Class ]:
6.1
[ HS Code ]:
29214210
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2921420090
[ Summary ]:
HS:2921420090 aniline derivatives and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
Chemosphere 90(2) , 270-5, (2013)
In this study we explore the relationship between solution pH and the distribution of the binding interactions at different domains of a dissolved humic acid (HA) for three xenobiotics: pentafluoroani...
Molecular rearrangement reactions in the gas phase triggered by electron attachment.Phys. Chem. Chem. Phys. 15(13) , 4754-66, (2013)
Bond formation and rearrangement reactions in gas phase electron attachment were studied through dissociative electron attachment (DEA) to pentafluorotoluene (PFT), pentafluoroaniline (PFA) and pentaf...
Bioactivation of 4-fluorinated anilines to benzoquinoneimines as primary reaction products.Chem. Biol. Interact. 77(3) , 263-81, (1991)
Metabolism and bioactivation of fluoroanilines was studied both in vitro in microsomal systems and in vivo. 4-Fluoroaniline and pentafluoroaniline and their non-para fluorinated analogues were used as...