Dicalcium phosphate dihydrate

Names

[ Name ]:
Dicalcium phosphate dihydrate

[Synonym ]:
calcium monohydrogen phosphate
acid calcium monophosphate
calcium hydrogen phosphate dihydrate
dicalciurn phosphate
dicalcium phosphate
calcium monohydrogen phosphate dihydrate
BicalciuM phosphate
Di-tab
Calcium hydrogenphosphate dihydrate
Calciumhydrogenphosphate,dih
MFCD00149621
Calcium phosphate di
Dibasic calcium phosphate dihydrate
Calcium hydrogen phosphate hydrate (1:1:2)
dibasic calcium phosphate
EINECS 231-826-1
Calcium phosphate, dibasic, dihydrate
Bekapress D 2
DICALCIUM PHOSPHAT
hydrogen calcium orthophosphate
CALCIUM PHOSPH
dicalcium phosphate anhydrous
phosphoric acid calcium salt

Biological Activity

[Description]:

Calcium hydrogen phosphate dihydrate, also known as CHPD or DCPD.Calcium hydrogen phosphate dihydrate can be found quite frequently in urinary calculi stones. Calcium hydrogen phosphate dihydrate can be used as an excipient, such as diluent, adsorbent. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Madhurambal G, et al. Crystallization and thermal characterization of calcium hydrogen phosphate dihydrate crystals[J]. Journal of thermal analysis and calorimetry, 2009, 96(1): 73-76.

[2]. Elder DP, et al. Pharmaceutical excipients - quality, regulatory and biopharmaceutical considerations. Eur J Pharm Sci. 2016 May 25;87:88-99.

Chemical & Physical Properties

[ Density]:
2.31

[ Boiling Point ]:
158ºC at 760 mmHg

[ Melting Point ]:
109°C -H₂O

[ Molecular Formula ]:
CaH₅O₆P

[ Molecular Weight ]:
172.09

[ Exact Mass ]:
171.944962

[ PSA ]:
111.69000

[ Index of Refraction ]:
1.5394

[ Stability ]:
Stable. Incompatible with acids.

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
1

Synthetic Route

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Precursor & DownStream

Precursor

DownStream

Articles

Stone compositions in Turkey: an analysis according to gender and region.

Urology 82(3) , 532-7, (2013)

To evaluate the compositions of the kidney stones obtained from different regions of Turkey and to present the gender and regional differences.The study included 6453 kidney stones obtained from patie...

Investigation of internal structure of fine granules by microtomography using synchrotron X-ray radiation.

Int. J. Pharm. 445(1-2) , 93-8, (2013)

Computed tomography (CT) using synchrotron X-ray radiation was evaluated as a non-destructive structural analysis method for fine granules. Two kinds of granules have been investigated: a bromhexine h...

The theoretical and experimental study on dicalcium phosphate dehydrate loading with protocatechuic aldehyde.

J. Mol. Model. 16(7) , 1187-94, (2010)

The aim of this study is to investigate the interaction between dicalcium phosphate dihydrate (CaHPO(4) x 2H(2)O, DCPD) and Protocatechuic aldehyde (C(7)H(6)O(3), Pca), which is the water-soluble cons...

Related Compounds

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