1,2-Diaminopropane
Names
[ CAS No. ]:
78-90-0
[ Name ]:
1,2-Diaminopropane
[Synonym ]:
1,2-Diaminopropane
1,2-Propanediamine
EINECS 201-155-9
MFCD00008089
Chemical & Physical Properties
[ Density]:
0.87
[ Boiling Point ]:
119-120ºC
[ Melting Point ]:
-37ºC
[ Molecular Formula ]:
C3H10N2
[ Molecular Weight ]:
74.12490
[ Flash Point ]:
33ºC
[ Exact Mass ]:
74.08440
[ PSA ]:
52.04000
[ LogP ]:
0.69290
[ Vapour density ]:
2.6 (vs air)
[ Vapour Pressure ]:
14 mm Hg ( 20 °C)
[ Index of Refraction ]:
1.445-1.447
[ Stability ]:
Stable. Flammable. Incompatible with strong oxidizing agents, acids, acid chlorides, acid anhydrides.
[ Water Solubility ]:
SOLUBLE
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TX6650000
- CHEMICAL NAME :
- 1,2-Propanediamine
- CAS REGISTRY NUMBER :
- 78-90-0
- BEILSTEIN REFERENCE NO. :
- 0605274
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 12
- MOLECULAR FORMULA :
- C3-H10-N2
- MOLECULAR WEIGHT :
- 74.15
- WISWESSER LINE NOTATION :
- ZY1&1Z
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Open irritation test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 10,61,1954
- TYPE OF TEST :
- Open irritation test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 3/12/1969
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,441,1986
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 3/12/1969
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,441,1986 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2230 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 3/12/1969
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 909 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ZEPTAT Zeitschrift fuer Experimentelle Pathologie und Therapie. (Berlin, Ger.) V.1-22, 1905-21. For publisher information, see REXMAS. Volume(issue)/page/year: 17,59,1915
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 593 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 97,1117,1977
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 500 uL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 10,61,1954 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83465 No. of Facilities: 118 (estimated) No. of Industries: 7 No. of Occupations: 13 No. of Employees: 2614 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83465 No. of Facilities: 122 (estimated) No. of Industries: 3 No. of Occupations: 8 No. of Employees: 8346 (estimated) No. of Female Employees: 3070 (estimated)
Safety Information
[ Symbol ]:
GHS02, GHS05, GHS06, GHS08
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H226-H302-H311-H314-H317-H334
[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338-P310
[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
C:Corrosive;
[ Risk Phrases ]:
R10;R21/22;R35
[ Safety Phrases ]:
S26-S37/39-S45
[ RIDADR ]:
UN 2258
[ WGK Germany ]:
1
[ RTECS ]:
TX6650000
[ Packaging Group ]:
II
[ Hazard Class ]:
8
[ HS Code ]:
29212900
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 29212900
Articles
Nucl. Med. Biol. 41(10) , 813-24, (2014)
(99m)Tc-Teboroxime ([(99m)TcCl(CDO)(CDOH)2BMe]) is a member of the BATO (boronic acid adducts of technetium dioximes) class of (99m)Tc(III) complexes. This study sought to explore the impact of co-lig...
Fluorescent carbon nanodots for sensitive and selective detection of tannic acid in wines.Talanta 132 , 252-7, (2014)
Herein we describe an easy one step synthesis of carbon nanodots (C-dots) by thermal carbonization of 6-bromohexylboronic acid using two different amine compounds, polyethyleneglycol bis(3-aminopropyl...
Capillary gas chromatographic determination of methylglyoxal from serum of diabetic patients by precolumn derivatization with 1,2-diamonopropane.J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 873(1) , 15-9, (2008)
Capillary gas chromatographic (GC) determination of methylglyoxal (MGo) was developed on the basis of precolumn derivatization with 1,2-diaminopropane (DAP) at pH 3. The elution was carried out on an ...