Hydroxylamine

Names

[ CAS No. ]:
7803-49-8

[ Name ]:
Hydroxylamine

[Synonym ]:
MFCD00044522
Hydroxylamine
EINECS 232-259-2
hydroxyl amine
Hydroxylamine solution

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
56.5±9.0 °C at 760 mmHg

[ Melting Point ]:
7°C

[ Molecular Formula ]:
H₃NO

[ Molecular Weight ]:
33.030

[ Exact Mass ]:
33.021465

[ PSA ]:
46.25000

[ LogP ]:
-0.81

[ Vapour Pressure ]:
179.1±0.2 mmHg at 25°C

[ Index of Refraction ]:
1.395

[ Stability ]:
Stable. Incompatible with oxidizing agents, potassium dichromate, chromium trioxide, zinc, calcium, copper, sodium, ammonia, carbonyls, phosphorus halides, pyridine, hypochlorites.

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NC2975000

CHEMICAL NAME :: Hydroxylamine

CAS REGISTRY NUMBER :: 7803-49-8

LAST UPDATED :: 199710

DATA ITEMS CITED :: 49

MOLECULAR FORMULA :: H3-N-O

MOLECULAR WEIGHT :: 33.04

WISWESSER LINE NOTATION :: ZQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 59 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 29 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 60 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 175 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: Sex chromosome loss and nondisjunction

MUTATION DATA

TYPE OF TEST :: Cytogenetic analysis

TEST SYSTEM :: Human Leukocyte

DOSE/DURATION :: 25 mg/L

REFERENCE :: CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 6,375,1973 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84783 No. of Facilities: 116 (estimated) No. of Industries: 3 No. of Occupations: 5 No. of Employees: 1722 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84783 No. of Facilities: 112 (estimated) No. of Industries: 5 No. of Occupations: 9 No. of Employees: 2689 (estimated) No. of Female Employees: 1481 (estimated)

Safety Information

[ Symbol ]:

GHS05, GHS07, GHS08, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H290-H302-H315-H317-H318-H335-H351-H373-H400

[ Precautionary Statements ]:
P261-P273-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn:Harmful;N:Dangerousfortheenvironment;

[ Risk Phrases ]:
R5;R22;R37/38;R41;R43;R48/22;R50

[ Safety Phrases ]:
S23-S26-S36/37/39-S47-S61-S22

[ RIDADR ]:
UN 3082 9/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
NC2975000

[ Packaging Group ]:
II

[ Hazard Class ]:
8

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

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A unique characteristic of mammalian sperm thermotaxis is extreme temperature sensitivity, manifested by the capacity of spermatozoa to respond to temperature changes of <0.0006 °C as they swim their ...

Sulfur amino acid metabolism in Zucker diabetic fatty rats.

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Delays between tissue collection and tissue fixation result in ischemia and ischemia-associated changes in protein phosphorylation levels, which can misguide the examination of signaling pathway statu...

Related Compounds

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