fluxofenim
Names
[ CAS No. ]:
88485-37-4
[ Name ]:
fluxofenim
[Synonym ]:
(1Ξ)-1-(4-chlorophenyl)-N-(1,3-dioxolan-2-ylmethoxy)-2,2,2-trifluoroethan-1-imine
(4-chlorobenzoylmethylene)triphenylphosphorane
1-(4-Chlorophenyl)-2-(3-pyridinyl)ethanone
1-(4-chlorophenyl)-2-(triphenylphosphanylidene)ethanone
Ph3P=COC6H4Cl
1-(4-chlorophenyl)-2-(triphenylphosphosphanylidene)ethanone
1-(4-chlorophenyl)-2-(triphenylphosphoranylidene)ethanone
1-(4-chlorophenyl)-2,2,2-trifluoro-1-ethanone O-(1,3-dioxolan-2-ylmethyl)oxime
4’-chloro-2,2,2-trifluoroacetophenone (EZ)-O-1,3-dioxolan-2-ylmethyloxime
1-(4-chloro-phenyl)-2-pyridin-3-yl-ethanone
(p-Chlorobenzoylmethylene)triphenylphosphorane
[(p-chlorobenzoyl)methylene]triphenylphosphoran
1-(4-chlorophenyl)-1-(1,3-dioxolan-2-ylmethoximino)-2,2,2-trifluoroethane
(pyrid-3-ylmethyl)-(4-chlorophenyl)-ketone
(1Z)-1-(4-Chlorophenyl)-N-(1,3-dioxolan-2-ylmethoxy)-2,2,2-triflu oroethanimine
1-(4-chlorophenyl)-2,2,2-trifluoroethanone O-(1,3-dioxolan-2-ylmethyl)oxime
4'-chloro-2-(3-pyridyl)-acetophenone
1-(4-CHLOROPHENYL)-2-(3-PYRIDYL)ETHANONE
Chemical & Physical Properties
[ Density]:
1.43g/cm3
[ Boiling Point ]:
309.5ºC at 760 mmHg
[ Melting Point ]:
25°C
[ Molecular Formula ]:
C12H11ClF3NO3
[ Molecular Weight ]:
309.66900
[ Flash Point ]:
141ºC
[ Exact Mass ]:
309.03800
[ PSA ]:
40.05000
[ LogP ]:
2.99590
[ Index of Refraction ]:
1.509
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- KM5638200
- CHEMICAL NAME :
- Ethanone, 1-(4-chlorophenyl)-2,2,2-trifluoro-, O-(1,3-dioxolan-2-ylmethyl)oxime
- CAS REGISTRY NUMBER :
- 88485-37-4
- LAST UPDATED :
- 199806
- DATA ITEMS CITED :
- 8
- MOLECULAR FORMULA :
- C12-H11-Cl-F3-N-O3
- MOLECULAR WEIGHT :
- 309.69
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 669 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C79,1991
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >1210 mg/m3/4H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-1190-1081 FLWP
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1540 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,430,1991
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 1544 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C79,1991
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 1480 mg/kg
- TOXIC EFFECTS :
- Gastrointestinal - hypermotility, diarrhea Gastrointestinal - other changes Musculoskeletal - other changes
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0535321 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 10500 mg/kg/4W-C
- TOXIC EFFECTS :
- Behavioral - food intake (animal) Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death
- REFERENCE :
- EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-1190-1081 FLWP
Safety Information
[ Symbol ]:
GHS06, GHS09
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H302-H312-H315-H330-H400
[ Precautionary Statements ]:
P260-P273-P280-P284-P310
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xn: Harmful;N: Dangerous for the environment;
[ Risk Phrases ]:
R21/22
[ Safety Phrases ]:
36/37/39-60-61
[ RIDADR ]:
UN3082 9/PG 3
[ RTECS ]:
KM5638200
Articles
J. Environ. Sci. Health B 44(8) , 805-9, (2009)
The expression of glutathione S-transferase (GST) activity in Festuca arundinacea was investigated in response to the following herbicide safeners: benoxacor, cloquintocet-mexyl, fenchlorazol-ethyl, f...
Induction of glutathione S-transferases in Arabidopsis by herbicide safeners.Plant Physiol. 130(3) , 1497-505, (2002)
Herbicide safeners increase herbicide tolerance in cereals but not in dicotyledenous crops. The reason(s) for this difference in safening is unknown. However, safener-induced protection in cereals is ...
Organ-specific expression of glutathione S-transferases and the efficacy of herbicide safeners in Arabidopsis.Plant Physiol. 140(1) , 167-75, (2006)
The functions of plant glutathione S-transferases (GSTs) under normal growth conditions are poorly understood, but their activity as detoxification enzymes has been harnessed in agriculture for select...