2-Ethylphenol

Names

[ CAS No. ]:
90-00-6

[ Name ]:
2-Ethylphenol

[Synonym ]:
o-ethylphenol
ortho-ethylphenol
2-Et-C6H4OH
2-Ethylphenol
Phenazine,2-ethyl
EINECS 201-958-4
2-Ethylphenazin
ethyl-Phenol
2-ethyl-phenazine
o-Hydroxyethylbenzene
MFCD00002249
Phenol, 2-ethyl-
2-ETHYL PHENOL
PHENOL,2-ETHYL

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
204.5±0.0 °C at 760 mmHg

[ Melting Point ]:
−18 °C(lit.)

[ Molecular Formula ]:
C₈H₁₀O

[ Molecular Weight ]:
122.164

[ Flash Point ]:
78.3±0.0 °C

[ Exact Mass ]:
122.073166

[ PSA ]:
20.23000

[ LogP ]:
2.47

[ Vapour Pressure ]:
0.2±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.537

[ Stability ]:
Stable. Combustible. Incompatible with acid chlorides, acid anhydrides, oxidizing agents.

[ Water Solubility ]:
insoluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SL4025000

CHEMICAL NAME :: Phenol, o-ethyl-

CAS REGISTRY NUMBER :: 90-00-6

BEILSTEIN REFERENCE NO. :: 1099397

LAST UPDATED :: 199712

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C8-H10-O

MOLECULAR WEIGHT :: 122.18

WISWESSER LINE NOTATION :: QR B2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 30,147,1975

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 172 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 18,868,1975 ** TUMORIGENIC DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3100 mg/kg/12W-I

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Skin and Appendages - tumors

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 19,413,1959 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M2496 No. of Facilities: 19 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 210 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M2496 No. of Facilities: 72 (estimated) No. of Industries: 3 No. of Occupations: 11 No. of Employees: 1775 (estimated) No. of Female Employees: 516 (estimated)

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H315-H318-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
C:Corrosive

[ Risk Phrases ]:
R20/21/22;R34

[ Safety Phrases ]:
S36/37/39-S45-S26

[ RIDADR ]:
UN 3145 8/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
SL4025000

[ Packaging Group ]:
III

[ Hazard Class ]:
8

[ HS Code ]:
29071900

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2907199090

[ Summary ]:
2907199090 other monophenols VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

Hydroxycinnamic acids used as external acceptors of electrons: an energetic advantage for strictly heterofermentative lactic acid bacteria.

Appl. Environ. Microbiol. 80(24) , 7574-82, (2014)

The metabolism of hydroxycinnamic acids by strictly heterofermentative lactic acid bacteria (19 strains) was investigated as a potential alternative energy route. Lactobacillus curvatus PE5 was the mo...

Cellular apoptosis and cytotoxicity of phenolic compounds: a quantitative structure-activity relationship study.

J. Med. Chem. 48 , 7234-42, (2005)

In this comprehensive study on the caspase-mediated apoptosis-inducing effect of 51 substituted phenols in a murine leukemia cell line (L1210), we determined the concentrations needed to induce caspas...

Simple and sensitive GC/MS-method for the quantification of urinary phenol, o- and m-cresol and ethylphenols as biomarkers of exposure to industrial solvents.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 995-996 , 93-100, (2015)

We have developed and validated a simple and sensitive method for the determination of urinary phenol as well as the urinary metabolites of toluene and ethylbenzene in one analytical run. After enzyma...

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.