2-Chloro-4-aminotoluene
Names
[ CAS No. ]:
95-74-9
[ Name ]:
2-Chloro-4-aminotoluene
[Synonym ]:
4-Amino-2-chlorotoluene
4-methyl-5-chloroaniline
3-chloro-4-methylphenylamine
2B oil
CPT
EINECS 202-446-3
3-CHLORO-P-TOLUIDINE
4-Methyl-3-chloroaniline
2-Chloro-4-Aminotoluene Or O-Chloro-P-Aminotoluene
DKC 1347
MFCD00007773
2-chloro-4-amino-toluene
3-CHLOR-4-METHYLANILIN
2-Chloro-4-aminotoluene
1-Amino-3-chloro-4-methylbenzene
3-Chloro-4-methylanilin
2-CHLORO-4-TOLUIDINE
3-CHLORO-4-METHYLANILINE D
3-cpt
DRC 1339
Benzenamine, 3-chloro-4-methyl-
3-Chloro-4-methylaniline
O-CHLORO-P-TOLUIDINE
drc1347
OCPT
Starlicide
cpt[qr]
3-CHLORO-P-TOLUIDINE (NH2=1)
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
243.1±20.0 °C at 760 mmHg
[ Melting Point ]:
25 °C
[ Molecular Formula ]:
C7H8ClN
[ Molecular Weight ]:
141.598
[ Flash Point ]:
100.8±21.8 °C
[ Exact Mass ]:
141.034531
[ PSA ]:
26.02000
[ LogP ]:
2.27
[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C
[ Index of Refraction ]:
1.585
[ Storage condition ]:
2-8°C
[ Stability ]:
Stable. Combustible. Incompatible with strong oxidizing agents, acid chlorides, acids, acid anhydrides, chloroformates, reducing agents.
[ Water Solubility ]:
1 g/L (20 ºC)
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- XU5111000
- CHEMICAL NAME :
- p-Toluidine, 3-chloro-
- CAS REGISTRY NUMBER :
- 95-74-9
- BEILSTEIN REFERENCE NO. :
- 0636511
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 15
- MOLECULAR FORMULA :
- C7-H8-Cl-N
- MOLECULAR WEIGHT :
- 141.61
- WISWESSER LINE NOTATION :
- ZR CG D1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 325 mg/kg
- TOXIC EFFECTS :
- Behavioral - muscle weakness Lungs, Thorax, or Respiration - dyspnea Lungs, Thorax, or Respiration - cyanosis
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 48 mg/kg
- TOXIC EFFECTS :
- Behavioral - muscle weakness Lungs, Thorax, or Respiration - dyspnea Lungs, Thorax, or Respiration - cyanosis
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 316 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - pigeon
- DOSE/DURATION :
- 13 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - quail
- DOSE/DURATION :
- 1 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - wild bird species
- DOSE/DURATION :
- 2400 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- Unscheduled DNA synthesis
- TYPE OF TEST :
- Mutation test systems - not otherwise specified
MUTATION DATA
- TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 200 mg/kg
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 46,305,1977
Safety Information
[ Symbol ]:
GHS06, GHS09
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H301 + H311-H315-H317-H319-H410
[ Precautionary Statements ]:
P273-P280-P301 + P310-P305 + P351 + P338-P312-P501
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
[ Hazard Codes ]:
Xn:Harmful
[ Risk Phrases ]:
R22;R36/37/38;R50/53
[ Safety Phrases ]:
S36/37/39-S45-S61-S60-S36/37-S26
[ RIDADR ]:
UN 2239 6.1/PG 3
[ WGK Germany ]:
2
[ RTECS ]:
XU5111000
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Articles
Gig. Tr. Prof. Zabol. (1) , 43-4, (1980)
Pathological features of 3-chloro-4-methyl benzamine HCl toxicity in rooks (Corvus frugilegus L.) and pheasants (Phasianus colchicus L.).
Gegenbaurs Morphol. Jahrb. 128(5) , 753-61, (1982)
Gross and microscopic changes in response to single po. doses of avicide 3-chloro-4-methyl benzamine HCl were studied in rooks (Corvus frugilegus L.) and pheasants (Phasianus colchicus L.). The observ...
Stabilization of the avicide 3-chloro-p-toluidine as the beta-cyclodextrin adduct.J. Agric. Food Chem. 47(7) , 2904-7, (1999)
Stabilization of the avicide 3-chloro-p-toluidine (CPTH) on rice baits by pseudo latex polymeric coating and beta-cyclodextin inclusion was investigated. When CPTH-treated rice baits were exposed to s...