2-Amino-p-xylene
Names
[ CAS No. ]:
95-78-3
[ Name ]:
2-Amino-p-xylene
[Synonym ]:
p-Dimethylaniline
Benzenamine,2,5-dimethyl
EINECS 202-451-0
1-amino-2,5-dimethylbenzene
2,5-di-methyl amino benzene
ZR B1 E1
5-Methyl-o-toluidine
MFCD00007743
2,5-dimethyl-aniline
6-Methyl-m-toluidine
p-Xylidine
2,5-Xylidine
2,5-dimethylbenzeneamine
2-Amino-1,4-dimethylbenzene
2,5-Dimethylaniline
o-amino-p-xylene
Benzenamine, 2,5-dimethyl-
2,5-Dimethylbenzenamine
2-Amino-p-xylene
Chemical & Physical Properties
[ Density]:
1.0±0.1 g/cm3
[ Boiling Point ]:
214.9±9.0 °C at 760 mmHg
[ Melting Point ]:
11.5 °C(lit.)
[ Molecular Formula ]:
C8H11N
[ Molecular Weight ]:
121.180
[ Flash Point ]:
93.9±0.0 °C
[ Exact Mass ]:
121.089149
[ PSA ]:
26.02000
[ LogP ]:
1.86
[ Vapour Pressure ]:
0.2±0.4 mmHg at 25°C
[ Index of Refraction ]:
1.559
[ Water Solubility ]:
<0.1 g/100 mL at 18 ºC
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- ZE9100000
- CHEMICAL NAME :
- 2,5-Xylidine
- CAS REGISTRY NUMBER :
- 95-78-3
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 12
- MOLECULAR FORMULA :
- C8-H11-N
- MOLECULAR WEIGHT :
- 121.20
- WISWESSER LINE NOTATION :
- ZR B1 E1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1297 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 841 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 13300 mg/kg/4W-I
- TOXIC EFFECTS :
- Liver - other changes Liver - changes in liver weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases
MUTATION DATA
- TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 200 mg/kg
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 46,305,1977 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 16,377,1978 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 16,377,1978 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987
Safety Information
[ Symbol ]:
GHS06, GHS08, GHS09
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H301 + H311 + H331-H373-H411
[ Precautionary Statements ]:
P261-P273-P280-P301 + P310-P311
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
T:Toxic;N:Dangerousfortheenvironment;
[ Risk Phrases ]:
R23/24/25;R33;R51/53
[ Safety Phrases ]:
S28-S36/37-S45-S61-S28A
[ RIDADR ]:
UN 1711 6.1/PG 2
[ WGK Germany ]:
3
[ RTECS ]:
ZE9100000
[ Packaging Group ]:
II
[ Hazard Class ]:
6.1
[ HS Code ]:
2921499090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2921430090
[ Summary ]:
HS:2921430090 toluidines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
J. Chromatogr. A. 1216(41) , 6970-3, (2009)
The assessment of human exposure to specific isomers of dimethylanilines (DMA's) is of interest for the evaluation of potential exposure-health outcome relationships. Improved analytical methods will ...
Determination method for xylidines in workplace air.J. Occup. Health 53(3) , 230-3, (2011)
The purpose of this research was to develop a determination method for xylidines (XLDs) in workplace air for risk assessment.The characteristics of the proposed method, such as recovery, detection lim...
Oxidation of 2, 5-dimethylaniline in NH 4 F· 2.35 HF medium Characteristics of the resulting conducting polymer. Genies EM and Noel P.J. Electroanal. Chem. Interfac. Electrochem. 296(2) , 473-490, (1990)