N-LAUROYLSARCOSINE

Names

[ CAS No. ]:
97-78-9

[ Name ]:
N-LAUROYLSARCOSINE

[Synonym ]:
EINECS 202-608-3
MFCD00021749
n-lauroylsarcosine

Biological Activity

[Description]:

N-lauroylsarcosine (NLS) is an anionic surfactant, and can be used as a permeation enhancer. The mixture of NLS in 25–50% ethanol acts synergistically to increase skin permeability, which may be useful for transdermal drug delivery research[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Yeu-Chun Kim, et al. Synergistic enhancement of skin permeability by N-lauroylsarcosine and ethanol. Int J Pharm. 2008 Mar 20;352(1-2):129-38.

Chemical & Physical Properties

[ Density]:
0.986g/cm3

[ Boiling Point ]:
413.2ºC at 760mmHg

[ Melting Point ]:
45-49 °C

[ Molecular Formula ]:
C₁₅H₂₉NO₃

[ Molecular Weight ]:
271.39600

[ Exact Mass ]:
271.21500

[ PSA ]:
57.61000

[ LogP ]:
3.45030

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
2811.0

[ WGK Germany ]:
1

[ Hazard Class ]:
6.1

[ HS Code ]:
2924199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924199090

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Molecular characterisation of clinical and environmental isolates of Mycobacterium kansasii isolates from South African gold mines.

J. Water Health 13 , 190-202, (2015)

Mycobacterium kansasii (M. kansasii) is a major cause of non-tuberculous mycobacterial pulmonary disease in the South African gold-mining workforce, but the source of infection and molecular epidemiol...

Improved enrichment and proteomic identification of outer membrane proteins from a Gram-negative bacterium: focus on Caulobacter crescentus.

Proteomics 12(2) , 251-62, (2012)

Efforts to characterize proteins found in the outer membrane (OM) of Gram-negative bacteria have been steadily increasing due to the promise of expanding our understanding of fundamental bacterial pro...

Correlating antimicrobial activity and model membrane leakage induced by nylon-3 polymers and detergents.

Soft Matter 11 , 6840-51, (2015)

Most antimicrobial peptides act upon target microorganisms by permeabilizing their membranes. The mode of action is often assessed by vesicle leakage experiments that use model membranes, with the ass...

Related Compounds

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