55612-21-0

55612-21-0 structure
55612-21-0 structure
  • Name: 2'-Deoxy-2'-fluoro-5-iodouridine
  • Chemical Name: 1-[(3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione
  • CAS Number: 55612-21-0
  • Molecular Formula: C9H10FIN2O5
  • Molecular Weight: 372.09
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
  • Create Date: 2016-01-10 04:54:14
  • Modify Date: 2024-01-31 10:30:40
  • 2'-Deoxy-2'-fluoro-5-iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name 1-[(3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione
Synonyms 5-Iodo-1-(2-fluoro-2-deoxy-β-D-ribofuranosyl)uracil
Uridine, 2'-deoxy-2'-fluoro-5-iodo-
Uridine,2'-deoxy-2'-fluoro-5-iodo
2'-Deoxy-2'-fluoro-5-iodouridine
5-Ifdu
2`-epi-Fialuridine
Description 2'-Deoxy-2'-fluoro-5-iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Density 2.2±0.1 g/cm3
Melting Point 216-218 °C
Molecular Formula C9H10FIN2O5
Molecular Weight 372.09
Exact Mass 371.961823
PSA 104.81000
LogP -0.32
Index of Refraction 1.685
Storage condition 2-8℃