52819-96-2

52819-96-2 structure

Name: aflatoxin Q1
Chemical Name: aflatoxin Q1
CAS Number: 52819-96-2
Molecular Formula: C₁₇H₁₂O₇
Molecular Weight: 328.27
Catalog: Signaling Pathways Anti-infection Fungal
Create Date: 2016-12-19 08:05:23
Modify Date: 2024-01-24 10:19:18
Aflatoxin Q1 is a hydroxy metabolite of Aflatoxin B1 (AFB1), which is a mycotoxin produced by Aspergillus flavus (A. flavus). Aflatoxin Q1, as well as and aflatoxin B1 8,9-oxide, is the major oxidative products formed from aflatoxin B1 in human liver microsomes, at all substrate concentrations. the 3 alpha-hydroxylation of aflatoxin B1 to aflatoxin Q1 is a potentially significant detoxication pathway[1][2].

Name	aflatoxin Q1
Synonyms	Aflatoxin Q1 3-hydroxy-Aflatoxin B1

Description	Aflatoxin Q1 is a hydroxy metabolite of Aflatoxin B1 (AFB1), which is a mycotoxin produced by Aspergillus flavus (A. flavus). Aflatoxin Q1, as well as and aflatoxin B1 8,9-oxide, is the major oxidative products formed from aflatoxin B1 in human liver microsomes, at all substrate concentrations. the 3 alpha-hydroxylation of aflatoxin B1 to aflatoxin Q1 is a potentially significant detoxication pathway[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal
References	[1]. Raney KD, et al. Oxidation of aflatoxins and sterigmatocystin by human liver microsomes: significance of aflatoxin Q1 as a detoxication product of aflatoxin B1. Chem Res Toxicol. 1992 Mar-Apr;5(2):202-10. [2]. Yamada M, et al. Detoxification of Aflatoxin B1 Contaminated Maize Using Human CYP3A4. J Microbiol Biotechnol. 2020 Aug 28;30(8):1207-1213.

RIDADR	UN 3172