Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: clomethiazole ethane-1,2-disulfonate
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Purity: 98.0%
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1867-58-9

1867-58-9 structure

1867-58-9 structure

Name: clomethiazole ethane-1,2-disulfonate
Chemical Name: clomethiazole ethane-1,2-disulfonate
CAS Number: 1867-58-9
Molecular Formula: C₁₄H₂₂Cl₂N₂O₆S₄
Molecular Weight: 513.50000
Create Date: 2016-05-31 06:11:44
Modify Date: 2023-01-25 10:24:48

Name	clomethiazole ethane-1,2-disulfonate
Synonyms	clomethiazole chlormethiazole ethanedisulfonate ethane-1,2-disulphonic acid,compound with 5-(2-chloroethyl)-4-methylthiazole (1:2) clomethiazole edisylate chlormethiazole bis-5-(2-chloroethyl)-4-methylthiazole edisilate Clomethiazole ethanedisulfonate Heminevrin

Density	1.218g/cm3
Boiling Point	245.8ºC at 760mmHg
Molecular Formula	C₁₄H₂₂Cl₂N₂O₆S₄
Molecular Weight	513.50000
Flash Point	102.4ºC
Exact Mass	511.97400
PSA	207.76000
LogP	5.38920
Vapour Pressure	1.07E-23mmHg at 25°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KI3280000

CAS REGISTRY NUMBER :: 1867-58-9

LAST UPDATED :: 199706

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C6-H8-Cl-N-S.1/2C2-H6-O6-S2

MOLECULAR WEIGHT :: 256.74

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Human - woman

DOSE/DURATION :: 1560 mg/kg/4D-C

TOXIC EFFECTS :: Behavioral - coma Lungs, Thorax, or Respiration - respiratory depression

REFERENCE :: ICMED9 Intensive Care Medicine. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.3- 1977- Volume(issue)/page/year: 10,315,1984

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 835 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: APSXAS Acta Pharmaceutica Suecica. (Apotekarsocieteten-Farmacevtiska Foereningen, Box 1136, S-111, 81 Stockholm, Sweden) V.1- 1964- Volume(issue)/page/year: 4,269,1967

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 380 mg/kg

TOXIC EFFECTS :: Behavioral - sleep

REFERENCE :: FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 25,657,1962

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 620 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: APSXAS Acta Pharmaceutica Suecica. (Apotekarsocieteten-Farmacevtiska Foereningen, Box 1136, S-111, 81 Stockholm, Sweden) V.1- 1964- Volume(issue)/page/year: 4,269,1967

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 150 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: APSXAS Acta Pharmaceutica Suecica. (Apotekarsocieteten-Farmacevtiska Foereningen, Box 1136, S-111, 81 Stockholm, Sweden) V.1- 1964- Volume(issue)/page/year: 4,269,1967

HS Code	2934100090

HS Code	2934100090
Summary	2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%