2566-32-7

2566-32-7 structure

Name: N-Methyl-DL-valine
Chemical Name: N-methylvaline
CAS Number: 2566-32-7
Molecular Formula: C₆H₁₄ClNO₂
Molecular Weight: 167.634
Catalog: Biochemical Amino acids and their derivatives Proline derivatives
Create Date: 2018-09-07 17:29:31
Modify Date: 2024-01-11 19:33:16
N-Methyl-DL-valine is a valine derivant, is metabolized to cysteine, alanine, tyrosine, tryptophan, citric acid, and succinic acid in the sprout. N-Methyl-DL-valine involves in the modification of monomethyl auristatin F (MMAF), an anti-tubulin agent, makes it hydrophobic functionalization and increases cell permeability[1][2].

Name	N-methylvaline
Synonyms	methyl-valine N-Methylvaline hydrochloride N-METHYL-DL-VALINE HYDROCHLORIDE Valine, N-methyl-, hydrochloride (1:1) H-(S,R)-NMeVal-OH N-ME-DL-VAL-OH HCL N-Methyl-dl-valine,HCl N-methyl-valine N-Methylvaline hydrochloride (1:1)

Description	N-Methyl-DL-valine is a valine derivant, is metabolized to cysteine, alanine, tyrosine, tryptophan, citric acid, and succinic acid in the sprout. N-Methyl-DL-valine involves in the modification of monomethyl auristatin F (MMAF), an anti-tubulin agent, makes it hydrophobic functionalization and increases cell permeability[1][2].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. M. Pasteels, et al. Uptake and metabolism of [14C]rinderine and [14C]retronecine in leaf-beetles of the genus Platyphora and alkaloid accumulation in the exocrine defensive secretions. Chemoecology. 2003;13:55–62. [2]. Philip N Moquist, et al. Novel Auristatins with High Bystander and Cytotoxic Activities in Drug Efflux–positive Tumor Models. Mol Cancer Ther.2021;20(2): 320–328.

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RIDADR	NONH for all modes of transport
WGK Germany	3
HS Code	2922499990

HS Code	2922499990
Summary	HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%