17925-90-5

17925-90-5 structure

Name: (5E)-5-(dimethylaminohydrazinylidene)imidazole-4-carboxamide,hydrochloride
Chemical Name: (5E)-5-(dimethylaminohydrazinylidene)imidazole-4-carboxamide,hydrochloride
CAS Number: 17925-90-5
Molecular Formula: C₆H₁₁ClN₆O
Molecular Weight: 218.64400
Catalog: Research Areas Cancer
Create Date: 2016-10-13 23:37:56
Modify Date: 2024-02-26 11:39:10
Dacarbazine hydrochloride is a cell cycle nonspecific antineoplastic alkylating agent. Dacarbazine hydrochloride inhibits T and B lymphoblastic response, with IC50 values of 50 and 10 μg/mL, respectively. Dacarbazine hydrochloride can be used for the research of metastatic malignant melanoma[1][2].

Name	(5E)-5-(dimethylaminohydrazinylidene)imidazole-4-carboxamide,hydrochloride
Synonyms	5-(3,3-Dimethyl-1-triazeno)-1H-imidazole-4-carboxamide monohydrochloride Imidazole-4-carboxamide,5-(3,3-dimethyl-1-triazeno)-,monohydrochloride Dacarbazine HCl Dacarbazine hydrochloride

Description	Dacarbazine hydrochloride is a cell cycle nonspecific antineoplastic alkylating agent. Dacarbazine hydrochloride inhibits T and B lymphoblastic response, with IC50 values of 50 and 10 μg/mL, respectively. Dacarbazine hydrochloride can be used for the research of metastatic malignant melanoma[1][2].
Related Catalog	Research Areas >> Cancer
References	[1]. Rojo JM, et al. Inhibition of T and B lymphoblastic response by mithramycin, dacarbazine, prospidium chloride and peptichemio. Chemotherapy. 1983;29(5):345-51. [2]. Al-Badr AA, et al. Dacarbazine. Profiles Drug Subst Excip Relat Methodol. 2016;41:323-77.