168398-02-5
168398-02-5 structure
- Name: GR 203040
- Chemical Name: N-[[2-methoxy-5-(tetrazol-1-yl)phenyl]methyl]-2-phenylpiperidin-3-amine
- CAS Number: 168398-02-5
- Molecular Formula: C20H26Cl2N6O
- Molecular Weight: 437.37
- Catalog: Signaling Pathways GPCR/G Protein Neurokinin Receptor
- Create Date: 2017-09-09 09:29:09
- Modify Date: 2024-02-05 19:27:28
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GR203040 is an orally active NK1 receptor antagonist with a pKi of 10.3. GR203040 shows potent antiemetic activity[1].
| Name | N-[[2-methoxy-5-(tetrazol-1-yl)phenyl]methyl]-2-phenylpiperidin-3-amine |
|---|---|
| Synonyms |
3-Piperidinamine,N-[[2-methoxy-5-(1H-tetrazol-1-yl)phenyl]methyl]-2-phenyl-,hydrochloride(1:2),(2S,3S)
3-Piperidinamine,N-[[2-methoxy-5-(1H-tetrazol-1-yl)phenyl]methyl]-2-phenyl-,dihydrochloride,(2S-cis) 3-Piperidinamine,N-[[2-methoxy-5-(1H-tetrazol-1-yl)phenyl]methyl]-2-phenyl-,dihydrochloride,(2S,3S)-(9CI) |
| Description | GR203040 is an orally active NK1 receptor antagonist with a pKi of 10.3. GR203040 shows potent antiemetic activity[1]. |
|---|---|
| Related Catalog | |
| Target |
pKi: 10.3 (NK1 receptor)[1] |
| References |
| Boiling Point | 560.4ºC at 760mmHg |
|---|---|
| Molecular Formula | C20H26Cl2N6O |
| Molecular Weight | 437.37 |
| Flash Point | 292.7ºC |
| Exact Mass | 364.20100 |
| PSA | 76.89000 |
| LogP | 2.97350 |
| Vapour Pressure | 1.37E-12mmHg at 25°C |
| RIDADR | NONH for all modes of transport |
|---|