4130-19-2

4130-19-2 structure
4130-19-2 structure
  • Name: GP4G
  • Chemical Name: P1,P4-bis(5'-guanosyl) tetraphosphate
  • CAS Number: 4130-19-2
  • Molecular Formula: C20H28N10O21P4
  • Molecular Weight: 868.38600
  • Catalog: Research Areas Others
  • Create Date: 2017-11-02 01:26:11
  • Modify Date: 2024-01-11 11:38:52
  • GP4G (Diguanoside tetraphosphate) is a symmetrical bis-diphospho nucleoside that can be isolated from the cysts of Artemia salina. GP4G is an epithelial cell and hair growth regulator[1].

Name P1,P4-bis(5'-guanosyl) tetraphosphate
Synonyms P(1),P(4)-bis(5'-guanosyl) tetraphosphate
[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] hydrogen phosphate
Bis(5'-guanosyl) tetraphosphate
P1,P4-Bis(5'-guanosyl) tetraphosphate
guanosine(5')tetraphospho(5')guanosine
GP4G
bis(guanylyl) diphosphate
(ppG)2
GppppG
G(5')p4(5')G
Diguanosine tetraphosphate
Description GP4G (Diguanoside tetraphosphate) is a symmetrical bis-diphospho nucleoside that can be isolated from the cysts of Artemia salina. GP4G is an epithelial cell and hair growth regulator[1].
Related Catalog
Target

Human Endogenous Metabolite

In Vitro GP4G 可进入 Hela 和成纤维细胞,以双曲线饱和轮廓诱导 Hela 和成纤维细胞存活率的增加[1]。
In Vivo GP4G (约1 mL,外用于背侧区域,每天一次,持续28天)有利于 Wistar 大鼠的毛发生长[1]。 Animal Model: Wistar rats (n = 5)[1] Dosage: About 1 mL of the product was applied daily with a cotton swab over a period of 28 days. Administration: Topically applied to the dorsal region (8 cm2, shaved), daily with a cotton swab over a period of 28 days. Result: Favored hair growth.
References

[1]. Te Velthuis AJ, et al. Influenza virus RNA polymerase: insights into the mechanisms of viral RNA synthesis. Nat Rev Microbiol. 2016 Aug;14(8):479-93.  

Molecular Formula C20H28N10O21P4
Molecular Weight 868.38600
Exact Mass 868.03800
PSA 515.13000
Precursor  0

DownStream  2