Name | P1,P4-bis(5'-guanosyl) tetraphosphate |
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Synonyms |
P(1),P(4)-bis(5'-guanosyl) tetraphosphate
[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [[[(2R,3S,4R,5R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl] hydrogen phosphate Bis(5'-guanosyl) tetraphosphate P1,P4-Bis(5'-guanosyl) tetraphosphate guanosine(5')tetraphospho(5')guanosine GP4G bis(guanylyl) diphosphate (ppG)2 GppppG G(5')p4(5')G Diguanosine tetraphosphate |
Description | GP4G (Diguanoside tetraphosphate) is a symmetrical bis-diphospho nucleoside that can be isolated from the cysts of Artemia salina. GP4G is an epithelial cell and hair growth regulator[1]. |
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Related Catalog | |
Target |
Human Endogenous Metabolite |
In Vitro | GP4G 可进入 Hela 和成纤维细胞,以双曲线饱和轮廓诱导 Hela 和成纤维细胞存活率的增加[1]。 |
In Vivo | GP4G (约1 mL,外用于背侧区域,每天一次,持续28天)有利于 Wistar 大鼠的毛发生长[1]。 Animal Model: Wistar rats (n = 5)[1] Dosage: About 1 mL of the product was applied daily with a cotton swab over a period of 28 days. Administration: Topically applied to the dorsal region (8 cm2, shaved), daily with a cotton swab over a period of 28 days. Result: Favored hair growth. |
References |
Molecular Formula | C20H28N10O21P4 |
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Molecular Weight | 868.38600 |
Exact Mass | 868.03800 |
PSA | 515.13000 |