36752-54-2

36752-54-2 structure

Name: 10-Shogaol
Chemical Name: (E)-1-(4-hydroxy-3-methoxyphenyl)tetradec-4-en-3-one
CAS Number: 36752-54-2
Molecular Formula: C₂₁H₃₂O₃
Molecular Weight: 332.47700
Catalog: Signaling Pathways Immunology/Inflammation COX
Create Date: 2016-01-25 11:55:56
Modify Date: 2024-01-03 06:53:33
[10]-Shogaol is an antioxidant from Zingiber officinale for human skin cell growth and a migration enhancer. [10]-Shogaol inhibits COX-2 with an IC50 of 7.5 μM and has antiproliferation activity[1][2][3].

Name	(E)-1-(4-hydroxy-3-methoxyphenyl)tetradec-4-en-3-one
Synonyms	10-Shogaol

Description	[10]-Shogaol is an antioxidant from Zingiber officinale for human skin cell growth and a migration enhancer. [10]-Shogaol inhibits COX-2 with an IC50 of 7.5 μM and has antiproliferation activity[1][2][3].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Immunology/Inflammation >> COX
Target	COX-2:7.5 μM (IC50)
References	[1]. Chen CY, et al. 10-Shogaol, an antioxidant from Zingiber officinale for skin cell proliferation and migration enhancer. Int J Mol Sci. 2012;13(2):1762-77. [2]. van Breemen RB, et al. Cyclooxygenase-2 inhibitors in ginger (Zingiber officinale). Fitoterapia. 2011 Jan;82(1):38-43. [3]. Liu CM, et al. Ginger Phytochemicals Inhibit Cell Growth and Modulate Drug Resistance Factors in Docetaxel Resistant Prostate Cancer Cell. Molecules. 2017 Sep 5;22(9). pii: E1477.

RIDADR	NONH for all modes of transport