151070-83-6

151070-83-6 structure

Name: Immepip
Chemical Name: 4-(1h-imidazol-4-ylmethyl)-piperidine
CAS Number: 151070-83-6
Molecular Formula: C₉H₁₅N₃
Molecular Weight: 165.23500
Catalog: Signaling Pathways GPCR/G Protein Histamine Receptor
Create Date: 2018-12-27 18:34:35
Modify Date: 2024-01-12 11:58:14
Immepip is a H3 agonist. Immepip can reduce cortical histamine release. Immepip can be used for the research of neurological diseases[1].

Name	4-(1h-imidazol-4-ylmethyl)-piperidine

Description	Immepip is a H3 agonist. Immepip can reduce cortical histamine release. Immepip can be used for the research of neurological diseases[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> Histamine Receptor
In Vivo	Immepip (i.p.; 5, 10 mg/kg) 显著减少皮质组胺释放，但仅微弱地促进大鼠睡眠[1]。 Animal Model: Sprague-Dawley rats[1] Dosage: 5, 10 mg/kg Administration: Intraperitoneally Result: Significantly modulated brain histamine release and slight, albeit significant, decreased in sleep onset latency.
References	[1]. Yves Lamberty, et al. H3 agonist immepip markedly reduces cortical histamine release, but only weakly promotes sleep in the rat. Pharmacol Res. 2003 Aug;48(2):193-8.