97759-16-5

97759-16-5 structure

Name: S186
Chemical Name: Phosphonic acid, [1-(acetylamino)propylidene]bis-, calcium sodium salt (1:1:1)
CAS Number: 97759-16-5
Molecular Formula: C₅H₁₃CaNNaO₇P₂
Molecular Weight: 324.17500
Catalog: Research Areas Others
Create Date: 2016-06-12 09:29:38
Modify Date: 2024-01-19 20:01:28
S186 is a kind of sodium salts of calcium-acetylpropylamine phosphonate(APA); a new strontium-specific chelating agent.IC50 value:Target: In a case test for 4 person who took 90Sr in due to an internal contaminated accident, the APAP was adminstrated intramuscularly once a day for 3 days, the increase excretion of 90Sr was obvious and no side effects was observed among them. Recently, S186 has also been approved by Shanghai Municipal Health Bureau for emergency medical use in China.

Name	Phosphonic acid, [1-(acetylamino)propylidene]bis-, calcium sodium salt (1:1:1)
Synonyms	S186

Description	S186 is a kind of sodium salts of calcium-acetylpropylamine phosphonate(APA); a new strontium-specific chelating agent.IC50 value:Target: In a case test for 4 person who took 90Sr in due to an internal contaminated accident, the APAP was adminstrated intramuscularly once a day for 3 days, the increase excretion of 90Sr was obvious and no side effects was observed among them. Recently, S186 has also been approved by Shanghai Municipal Health Bureau for emergency medical use in China.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Others
References	[1]. Weihai Zhuo, et al. A Brief Review of Researches Related to Radiation Emergency Medicine at Fundan University, China. Radiation Emergency Medicine. 2012 Vol.1 No.1-2 7-10.