881415-72-1

881415-72-1 structure

Name: BS2G Crosslinker disodium
Chemical Name: Pentanedioic acid, 1,5-bis(2,5-dioxo-3-sulfo-1-pyrrolidinyl) ester, disodium salt
CAS Number: 881415-72-1
Molecular Formula: C₁₃H₁₂N₂Na₂O₁₄S₂
Molecular Weight: 509.37500
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
Create Date: 2017-10-18 16:49:35
Modify Date: 2024-01-09 15:30:31
BS2G Crosslinker (disodium) is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name	Pentanedioic acid, 1,5-bis(2,5-dioxo-3-sulfo-1-pyrrolidinyl) ester, disodium salt
Synonyms	3-Pyrrolidinesulfonic acid, 1,1'-[(1,5-dioxo-1,5-pentanediyl)bis(oxy)]bis[2,5-dioxo-, disodium salt Glutaric Acid Bis(3-Sulfo-N-hydroxysuccinimide Ester) Disodium Salt

Description	BS2G Crosslinker (disodium) is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Target	Non-cleavable
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References	[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.