29623-29-8

29623-29-8 structure

Name: 13-Oxo-9E,11E-octadecadienoic acid
Chemical Name: (9Z,11E/Z)-13-oxooctadecatrienoic acid
CAS Number: 29623-29-8
Molecular Formula: C₁₈H₃₀O₃
Molecular Weight: 294.42900
Catalog: Signaling Pathways Cell Cycle/DNA Damage PPAR
Create Date: 2018-12-27 19:23:13
Modify Date: 2024-01-11 20:03:06
13-Oxo-9E,11E-octadecadienoic acid, an isomer of 9-oxo-ODA, is a potent PPARα activator derived from tomato juice. 13-Oxo-9E,11E-octadecadienoic acid decreases plasma and hepatic triglyceride in obese diabetic mice[1].

Name	(9Z,11E/Z)-13-oxooctadecatrienoic acid
Synonyms	13-oxo-9Z,11E/Z-octadecadienoic acid 13-Oxo-9,11-octadecadiensaeure 13-Oxo-9E,11E-octadecadienoicacid 13-Oxo-9E,11E-octadecadienoic acid

Description	13-Oxo-9E,11E-octadecadienoic acid, an isomer of 9-oxo-ODA, is a potent PPARα activator derived from tomato juice. 13-Oxo-9E,11E-octadecadienoic acid decreases plasma and hepatic triglyceride in obese diabetic mice[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> PPAR
Target	PPARα
In Vivo	13-Oxo-9E,11E-octadecadienoic acid (feed; 0.02% and 0.05%; for 4 weeks) improves dyslipidemia and lowering TG content in the liver and skeletal muscle of HFD-fed KK-Ay mice[1]. Animal Model: Male KK-Ay mice with 4-week-old[1] Dosage: 0.02% and 0.05% Administration: Feed; for 4 weeks Result: Improved dyslipidemia and lowering TG content in the liver and skeletal muscle of HFD-fed KK-Ay mice.
References	[1]. Kim YI, et al. Potent PPARα activator derived from tomato juice, 13-oxo-9,11-octadecadienoic acid, decreasesplasma and hepatic triglyceride in obese diabetic mice. PLoS One. 2012;7(2):e31317.