147118-38-5
147118-38-5 structure
- Name: 7-[4-fluorophenyl]-6-isopropyl)-2-(N-Methyl-N-MethylSulfonyl amino)pyrimidine-5-yl]-(3R)-3-(terbutyldimethylsilyloxy)-5-oxo-6E-heptane acid,Methyl ester
- Chemical Name: 7-[4-fluorophenyl]-6-isopropyl)-2-(N-Methyl-N-MethylSulfonyl amino)pyrimidine-5-yl]-(3R)-3-(terbutyldimethylsilyloxy)-5-oxo-6E-heptane acid,Methyl ester
- CAS Number: 147118-38-5
- Molecular Formula: C29H42FN3O6SSi
- Molecular Weight: 607.809
- Create Date: 2018-09-27 11:49:46
- Modify Date: 2026-08-02 18:19:12
| Name | 7-[4-fluorophenyl]-6-isopropyl)-2-(N-Methyl-N-MethylSulfonyl amino)pyrimidine-5-yl]-(3R)-3-(terbutyldimethylsilyloxy)-5-oxo-6E-heptane acid,Methyl ester |
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| Synonyms |
(3R,6E)-3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-5-oxo-6-htenoic acid methyl ester
methyl (3R,6E)-3-{[tert-butyl(dimethyl)silyl]oxy}-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-(propan-2-yl)pyrimidin-5-yl]-5-oxohept-6-enoate (R,E)-Methyl 3-((tert-butyldimethylsilyl)oxy)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmet methyl 7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-(3R)-3-(tert-butyldimethylsilyloxy)-5-oxo-(E)-6-heptenate methyl 7-[4-(4-fluorofenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)-pyrimidin-5-yl]-(3R)-3-(tert-butyldimethylsilyloxy)-5-oxo-(E)-6-heptenate (3R,6E)-3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-5-oxo-6-heptenoic acid methyl ester (R,E)-Methyl 3-((tert-butyldiMethylsilyl)oxy)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-MethylMethylsulfonaMido)pyriMidin-5-yl)-5-oxoht-6-enoate (3R,6E)-3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-7-[4-(4-fl (3R,6E)-3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-5-oxo-6-htenoic acid methyl este 6-Htenoic acid, 3-[[(1,1-diMethylethyl)diMethylsilyl] oxy]-7-[4-(4-fluorophenyl)-6-(1-Methylethyl)-2-[Methyl (Methylsulfonyl)amino]-5-pyriMidinyl]-5-oxo-, Methyl ester, (3R,6E) (3R,6E)-3-[[(1,1-DiMethylethyl)diMethylsilyl]oxy]-7-[4-(4-fluorophenyl)-6-(1-Methylethyl)-2-[Methyl( (R,E)-Methyl 3-((tert-butyldimethylsilyl)oxy)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethyl Rosuvastatin calcium intermediate J8 6-Htenoic acid,3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-5-o (3R,6E)-3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-5-oxo-6-hte Statin intermediate J8 rui shu 6-Heptenoic acid,3-[[(1,1-diMethylethyl)diMethylsilyl] oxy]-7-[4-(4-fluorophenyl)-6-(1-Methylethyl)-2-[Methyl (Methylsulfonyl)aMino]-5-pyriMidinyl]-5-oxo-,Methyl ester,(3R,6E) Methyl (3R,6E)-3-{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-7-{4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl}-5-oxo-6-heptenoate Methyl 7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidine-5-yl]-(3R)-3-(tert-butyldimethylsilyloxy)-5-oxo-(6E)-htanoate Methyl 7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidine-5-yl]-(3R)-3-(tert-butyldimethylsilyloxy)-5-oxo-(6E)-heptanoate Methyl (3R,6E)-3-{[tert-butyl(dimethyl)silyl]oxy}-7-{4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-5-oxohept-6-enoate methyl (3R,6E)-3-[[(1,1-dimethylethyl)dimethylsilyl]-oxo]-7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidyl]-5-oxo-6-heptenoate 7-[4-Fluorophenyl]-6-isopropyl)-2-(N-methyl-N-methylsulfonyl amino)pyrimidine-5-yl]-(3R)-3-(tert-butyldimethylsilyloxy)-5-oxo-6E-htanoic acid methyl ester methyl 7-[4-(4-flourophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-(3R)-3-(tert-butyldimethylsilyloxy)-5-oxo-(E)-6-heptenoate methyl 7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-(3R)-3-(tert-butyldimethylsilyloxy)-5-oxo-(E)-6-heptenoate |
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 679.1±65.0 °C at 760 mmHg |
| Molecular Formula | C29H42FN3O6SSi |
| Molecular Weight | 607.809 |
| Flash Point | 364.5±34.3 °C |
| Exact Mass | 607.254761 |
| PSA | 124.14000 |
| LogP | 5.42 |
| Vapour Pressure | 0.0±2.1 mmHg at 25°C |
| Index of Refraction | 1.528 |
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| Literature: ORCHID CHEMICALS and PHARMACEUTICALS LIMITED Patent: WO2008/93205 A2, 2008 ; Location in patent: Page/Page column 7-8 ; |
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| Literature: Bioorganic and Medicinal Chemistry, , vol. 5, # 2 p. 437 - 444 |
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| Literature: Bioorganic and Medicinal Chemistry, , vol. 5, # 2 p. 437 - 444 |
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| Literature: Bioorganic and Medicinal Chemistry, , vol. 5, # 2 p. 437 - 444 |
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| Literature: Bioorganic and Medicinal Chemistry, , vol. 5, # 2 p. 437 - 444 |
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| Literature: Bioorganic and Medicinal Chemistry, , vol. 5, # 2 p. 437 - 444 |
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| Literature: Bioorganic and Medicinal Chemistry, , vol. 5, # 2 p. 437 - 444 |
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147118-38-5 |
| Literature: Bioorganic and Medicinal Chemistry, , vol. 5, # 2 p. 437 - 444 |
| Precursor 7 | |
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| DownStream 3 | |
