53005-05-3
53005-05-3 structure
- Name: 4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID
- Chemical Name: 4,4'-diisothiocyano-trans-stilbene-2,2'-disulfonic acid
- CAS Number: 53005-05-3
- Molecular Formula: C16H10N2O6S4
- Molecular Weight: 454.52000
- Catalog: Signaling Pathways Cell Cycle/DNA Damage RAD51
- Create Date: 2018-12-30 00:07:21
- Modify Date: 2025-08-25 17:19:57
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DIDS is a potent RAD51 inhibitor. DIDS inhibits the RAD51-mediated homologous pairing and strand-exchange reactions. DIDS inhibits anion exchange and binding to the red blood cell membrane[1][2].
| Name | 4,4'-diisothiocyano-trans-stilbene-2,2'-disulfonic acid |
|---|---|
| Synonyms |
dids
4,4'-Diisothiocyanostilbene-2,2'-disulfonic acid 4,4'-diisothiocyanato-stilbene-2,2'-disulfonic acid trans-4,4'-diisothiocyanatostilbene-2,2'-disulfonic acid 4,4'-diisothiocyanato-2,2'-stilbenedisulfoneic acid 4,4'-diisothiocyanostilbene-2-2'-disulphonic acid 5-isothiocyanato-2-[(E)-2-(4-isothiocyanato-2-sulfophenyl)ethenyl]benzenesulfonic acid 4,4'-Diisothiocyanato-2,2'-stilbenedisulfonic acid |
| Description | DIDS is a potent RAD51 inhibitor. DIDS inhibits the RAD51-mediated homologous pairing and strand-exchange reactions. DIDS inhibits anion exchange and binding to the red blood cell membrane[1][2]. |
|---|---|
| Related Catalog | |
| In Vitro | DIDS (0-10 μM) 抑制 RAD51 介导的链交换[1]。 DIDS (0-20 μM) 通过 RAD51 抑制 DNA 结合[1]。 DIDS (10 μM; 0-60 分钟) 在 DNA 不存在的情况下刺激 RAD51 的 ATP 水解活性[1]。 |
| References |
| Density | 1.54g/cm3 |
|---|---|
| Melting Point | >400ºC |
| Molecular Formula | C16H10N2O6S4 |
| Molecular Weight | 454.52000 |
| Exact Mass | 453.94200 |
| PSA | 214.40000 |
| LogP | 5.98060 |
| Index of Refraction | 1.693 |
| HS Code | 2930909090 |
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| HS Code | 2930909090 |
|---|---|
| Summary | 2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |