58717-24-1

58717-24-1 structure
58717-24-1 structure
  • Name: A2315A
  • Chemical Name: (3R,5S,6E,8E,13E,15R,16R,19R)-3,5-dihydroxy-7,15,19-trimethyl-16-propan-2-yl-17,24-dioxa-11,20,25-triazabicyclo[20.2.1]pentacosa-1(25),6,8,13,22-pentaene-12,18,21-trione
  • CAS Number: 58717-24-1
  • Molecular Formula: C26H37N3O7
  • Molecular Weight: 503.58800
  • Catalog: Research Areas Infection
  • Create Date: 2016-08-27 11:08:37
  • Modify Date: 2024-01-09 17:19:30
  • A2315A (Madumycin II) is an alanine-containing streptogramin A antibiotic. A2315A is a potent peptidyl transferase center (PTC) inhibitor. A2315A inhibits the ribosome prior to the first cycle of peptide bond formation[1].

Name (3R,5S,6E,8E,13E,15R,16R,19R)-3,5-dihydroxy-7,15,19-trimethyl-16-propan-2-yl-17,24-dioxa-11,20,25-triazabicyclo[20.2.1]pentacosa-1(25),6,8,13,22-pentaene-12,18,21-trione
Synonyms Antibiotic A 2315A
Madumycin II
A2315A
A-2315
Antibiotic A 2315
Madumicin II
Description A2315A (Madumycin II) is an alanine-containing streptogramin A antibiotic. A2315A is a potent peptidyl transferase center (PTC) inhibitor. A2315A inhibits the ribosome prior to the first cycle of peptide bond formation[1].
Related Catalog
References

[1]. Osterman IA, et, al. Madumycin II inhibits peptide bond formation by forcing the peptidyl transferase center into an inactive state. Nucleic Acids Res. 2017 Jul 7;45(12):7507-7514.  

Molecular Formula C26H37N3O7
Molecular Weight 503.58800
Exact Mass 503.26300
PSA 157.97000
LogP 2.12600