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298-51-1

298-51-1 structure
298-51-1 structure

Name 10H-Phenothiazine-10-carboxylicacid, 2-(diethylamino)ethyl ester, hydrochloride (1:1)
Synonyms Phenolphthalidin
Boiling Point 469.3ºC at 760 mmHg
Molecular Formula C19H23ClN2O2S
Molecular Weight 378.91600
Flash Point 237.6ºC
Exact Mass 378.11700
PSA 58.08000
LogP 5.63470
Vapour Pressure 5.57E-09mmHg at 25°C
Index of Refraction 1.612

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SN7350000
CHEMICAL NAME :
Phenothiazine-10-carboxylic acid, 2-(diethylamino)ethyl ester, hydrochloride
CAS REGISTRY NUMBER :
298-51-1
LAST UPDATED :
199803
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C19-H22-N2-O2-S.Cl-H
MOLECULAR WEIGHT :
378.95
WISWESSER LINE NOTATION :
T C666 BN ISJ BVO2N2&2 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
440 mg/kg
TOXIC EFFECTS :
Behavioral - sleep Behavioral - convulsions or effect on seizure threshold
REFERENCE :
APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 13,59,1957
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
140 mg/kg
TOXIC EFFECTS :
Behavioral - sleep Behavioral - convulsions or effect on seizure threshold
REFERENCE :
APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 13,59,1957
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
620 mg/kg
TOXIC EFFECTS :
Behavioral - sleep Behavioral - convulsions or effect on seizure threshold
REFERENCE :
APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 13,59,1957
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
26 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 90,241,1952
Precursor  2

DownStream  0