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Product Name: 1H-Pyrrolizine-3,5(2H,6H)-dione,dihydro-
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18356-28-0

18356-28-0 structure

18356-28-0 structure

Name: Rolziracetam
Chemical Name: 2,6,7,8-tetrahydro-1H-pyrrolizine-3,5-dione
CAS Number: 18356-28-0
Molecular Formula: C₇H₉NO₂
Molecular Weight: 139.15200
Catalog: Research Areas Neurological Disease
Create Date: 2016-02-22 22:40:40
Modify Date: 2026-09-22 12:02:06
Rolziracetam is a nootropic drug of the racetam family and improves short-term memory in rats and monkeys[1].

Name	2,6,7,8-tetrahydro-1H-pyrrolizine-3,5-dione
Synonyms	Rolziracetam, 10 mM in DMSO DIHYDRO-1H-PYRROLO[1,2-A]PYRROLE-3,5(2H,6H)-DIONE 7,7a-Dihydro-1H-pyrrolizine-3,5(2H,6H)-dione 1H-Pyrrolizine-3,5(2H,6H)-dione, dihydro 1-Azabicyclo[3.3.0]octane-2,8-dione 3,5-Dioxopyrrolizidine tetrahydro-pyrrolizine-3,5-dione Rolziracetam,CI 911,Inhibitor,CI911,inhibit dihydro-1H-Pyrrolizine-3,5(2H,6H)-dione CI-911 tetrahydro-6H-pyrrolizine-3,5-dione

Description	Rolziracetam is a nootropic drug of the racetam family and improves short-term memory in rats and monkeys[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease
References	[1]. Schindler U, et al. Pre-clinical evaluation of cognition enhancing drugs. Prog Neuropsychopharmacol Biol Psychiatry. 1989;13 Suppl:S99-115.

Density	1.28g/cm3
Boiling Point	274.9ºC at 760mmHg
Molecular Formula	C₇H₉NO₂
Molecular Weight	139.15200
Flash Point	130.5ºC
Exact Mass	139.06300
PSA	37.38000
LogP	0.23570
Vapour Pressure	0.00526mmHg at 25°C
Index of Refraction	1.548
Storage condition	2-8℃

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UY8000000

CHEMICAL NAME :: 1H-Pyrrolizine-3,5(2H,6H)-dione, dihydro-

CAS REGISTRY NUMBER :: 18356-28-0

BEILSTEIN REFERENCE NO. :: 0121236

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C7-H9-N-O2

MOLECULAR WEIGHT :: 139.17

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 7 gm/kg/14D-I

TOXIC EFFECTS :: Liver - other changes Kidney, Ureter, Bladder - other changes Musculoskeletal - other changes

REFERENCE :: TOPADD Toxicologic Pathology. (c/o Dr. F.A. de la Iglesia, Warner-Lambert Co., Pharmaceutical Research Div., POB 1047, Ann Arbor, MI 48106) V.6(3/4)- 1978- Volume(issue)/page/year: 17,545,1989

HS Code	2933990090

Precursor 9
81980-11-2 7766-83-8 7766-86-1 98547-95-6
502-50-1 67-56-1 64-17-5 108-24-7
7766-85-0
DownStream 3
7766-86-1 61772-94-9 643-20-9

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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