CHEMICAL IDENTIFICATION
-
RTECS NUMBER :
-
TP2494900
-
CHEMICAL NAME :
-
Platinum(II), dichloro(4,5-dimethyl-o-phenylenediammine)-, (SP-4-2)-
-
CAS REGISTRY NUMBER :
-
40580-75-4
-
LAST UPDATED :
-
199410
-
DATA ITEMS CITED :
-
2
-
MOLECULAR FORMULA :
-
C8-H12-Cl2-N2-Pt
-
MOLECULAR WEIGHT :
-
402.21
-
WISWESSER LINE NOTATION :
-
ZR BZ D1 E1 &G-PT-G
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
-
TYPE OF TEST :
-
LD50 - Lethal dose, 50 percent kill
-
ROUTE OF EXPOSURE :
-
Intraperitoneal
-
SPECIES OBSERVED :
-
Rodent - mouse
-
DOSE/DURATION :
-
283 mg/kg
-
TOXIC EFFECTS :
-
Kidney, Ureter, Bladder - other changes Tumorigenic - active as anti-cancer agent
MUTATION DATA
-
TYPE OF TEST :
-
Mutation in microorganisms
-
TEST SYSTEM :
-
Bacteria - Salmonella typhimurium
-
DOSE/DURATION :
-
10200 nmol/L
-
REFERENCE :
-
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 23,459,1980
|