26402-22-2

26402-22-2 structure

Name: Glyceryl monocaprate
Chemical Name: monocaprin
CAS Number: 26402-22-2
Molecular Formula: C₁₃H₂₆O₄
Molecular Weight: 246.34300
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2018-09-05 15:18:03
Modify Date: 2024-01-08 16:37:18
Glyceryl monocaprate (Monolaurin) is a 1-monoglyceride of capric acid against gram-positive bacterial infections[1]. Glyceryl monocaprate (Monolaurin) has inhibitory effect on Herpes Simplex Virus (HSV) and offers an effective treatment for herpes labialiss[2].

Name	monocaprin
Synonyms	1-Monodecanoyl Glycerol EINECS 247-667-6 Glycerol α-Monodecanoate 2,3-Dihydroxypropyl decanoate MFCD00056656

Description	Glyceryl monocaprate (Monolaurin) is a 1-monoglyceride of capric acid against gram-positive bacterial infections[1]. Glyceryl monocaprate (Monolaurin) has inhibitory effect on Herpes Simplex Virus (HSV) and offers an effective treatment for herpes labialiss[2].
Related Catalog	Signaling Pathways >> Anti-infection >> HSV Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
Target	IC50: Gram-positive Bacterial; HSV[1][2]
In Vitro	Glyceryl monocaprate (Monolaurin) has an antimicrobial activity against gram-positive ATCC SA 29123[1].
In Vivo	Glyceryl monocaprate (Monolaurin) combines with low-dose doxycycline offers an effective treatment for herpes labialiss, significantly reducing time to healing and pain compared with the placebo and monocaprin alone[2].
References	[1]. Chan WY, et al. In vitro antimicrobial activity of seven adjuvants against common pathogens associated with canine otitis externa.Vet Dermatol. 2019 Apr;30(2):133-e38. [2]. Skulason S, et al. A study of the clinical activity of a gel combining monocaprin and doxycycline: a novel treatment for herpes labialis.J Oral Pathol Med. 2012 Jan;41(1):61-7.

WGK Germany	1