Name | 6-Chloro-2-iodo-9-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)purine |
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Synonyms |
acetic acid (2r,3r,4r,5r)-3,4-diacetoxy-5-(6-chloro-2-iodo-purin-9-yl)-tetrahydro-furan-2-ylmethyl ester
MFCD03701153 |
Description | 6-Chloro-2-iodo-9-(2’,3’,5’-tri-O-acetyl-β-D-ribofuranosyl)purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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Related Catalog | |
References |
Density | 1.98g/cm3 |
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Boiling Point | 643.3ºC at 760 mmHg |
Melting Point | 181-183ºC |
Molecular Formula | C16H16ClIN4O7 |
Molecular Weight | 538.68 |
Flash Point | 342.9ºC |
Exact Mass | 537.97500 |
PSA | 131.73000 |
LogP | 1.40820 |
Index of Refraction | 1.713 |
~88% 5987-76-8 |
Literature: Gruenewald, Christian; Kwon, Taewoo; Piton, Nelly; Foerster, Ute; Wachtveitl, Josef; Engels, Joachim W. Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 1 p. 19 - 26 |
~85% 5987-76-8 |
Literature: Journal of Medicinal Chemistry, , vol. 35, # 2 p. 241 - 252 |
~% 5987-76-8 |
Literature: Nucleosides, Nucleotides and Nucleic Acids, , vol. 24, # 5-7 p. 717 - 720 |
~80% 5987-76-8 |
Literature: Journal of Medicinal Chemistry, , vol. 35, # 2 p. 241 - 252 |
~% 5987-76-8 |
Literature: Nucleosides, Nucleotides and Nucleic Acids, , vol. 24, # 5-7 p. 717 - 720 |
~62% 5987-76-8 |
Literature: Journal of Medicinal Chemistry, , vol. 35, # 2 p. 241 - 252 |
~% 5987-76-8 |
Literature: Bioorganic and Medicinal Chemistry, , vol. 12, # 11 p. 2995 - 3007 |
Precursor 6 | |
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DownStream 7 | |