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  • DC Chemicals Limited
  • China
  • Product Name: 776C85
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
  • Purity: 98.0%
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  • Contact: Tony Cao


59989-18-3

59989-18-3 structure
59989-18-3 structure
  • Name: Eniluracil
  • Chemical Name: 5-ethynyl-1H-pyrimidine-2,4-dione
  • CAS Number: 59989-18-3
  • Molecular Formula: C6H4N2O2
  • Molecular Weight: 136.10800
  • Catalog: Research Areas Cancer
  • Create Date: 2018-12-25 23:09:55
  • Modify Date: 2024-01-02 11:24:22
  • Eniluracil (5-Ethynyluracil), a uracil analogue and a mechanism-based irreversible inhibitor of dihydropyrimidine dehydrogenase (DPD), increases the oral bioavailability of 5-fluorouracil (5-FU) to 100%, facilitating uniform absorption and predictable toxicity[1].

Name 5-ethynyl-1H-pyrimidine-2,4-dione
Synonyms ethynyluracil
5-ETHYNYLURACIL
Compound 776C
Eniluracil
ethynyluracyl
GW776C85
776C85
Description Eniluracil (5-Ethynyluracil), a uracil analogue and a mechanism-based irreversible inhibitor of dihydropyrimidine dehydrogenase (DPD), increases the oral bioavailability of 5-fluorouracil (5-FU) to 100%, facilitating uniform absorption and predictable toxicity[1].
Related Catalog
Target

Dihydropyrimidine dehydrogenase[1]

References

[1]. Schilsky RL, et al. Eniluracil: an irreversible inhibitor of dihydropyrimidine dehydrogenase. Expert Opin Investig Drugs. 2000 Jul;9(7):1635-49.

Density 1.39g/cm3
Melting Point 320 °C(dec.)
Molecular Formula C6H4N2O2
Molecular Weight 136.10800
Exact Mass 136.02700
PSA 65.72000
Index of Refraction 1.589