Name | 5-ethynyl-1H-pyrimidine-2,4-dione |
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Synonyms |
ethynyluracil
5-ETHYNYLURACIL Compound 776C Eniluracil ethynyluracyl GW776C85 776C85 |
Description | Eniluracil (5-Ethynyluracil), a uracil analogue and a mechanism-based irreversible inhibitor of dihydropyrimidine dehydrogenase (DPD), increases the oral bioavailability of 5-fluorouracil (5-FU) to 100%, facilitating uniform absorption and predictable toxicity[1]. |
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Related Catalog | |
Target |
Dihydropyrimidine dehydrogenase[1] |
References |
Density | 1.39g/cm3 |
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Melting Point | 320 °C(dec.) |
Molecular Formula | C6H4N2O2 |
Molecular Weight | 136.10800 |
Exact Mass | 136.02700 |
PSA | 65.72000 |
Index of Refraction | 1.589 |
~97% 59989-18-3 |
Literature: Cooke, Jason W. B.; Bright, Robert; Coleman, Mark J.; Jenkins, Kevin P. Organic Process Research and Development, 2001 , vol. 5, # 4 p. 383 - 386 |
~72% 59989-18-3 |
Literature: Kundu, Nitya G.; Das, Biswajit; Majumdar, Anjali Synthesis, 1990 , # 3 p. 243 - 245 |
~% 59989-18-3 |
Literature: Journal of Heterocyclic Chemistry, , vol. 19, # 3 p. 463 - 464 |
~% 59989-18-3 |
Literature: Journal of Heterocyclic Chemistry, , vol. 19, # 3 p. 463 - 464 |
Precursor 4 | |
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DownStream 2 | |