28705-46-6

28705-46-6 structure

Name: Ethyl 7-(Diethylamino)coumarin-3-carboxylate
Chemical Name: ethyl 7-(diethylamino)-2-oxochromene-3-carboxylate
CAS Number: 28705-46-6
Molecular Formula: C₁₆H₁₉NO₄
Molecular Weight: 289.32600
Catalog: Signaling Pathways Neuronal Signaling Monoamine Oxidase
Create Date: 2019-01-12 19:20:11
Modify Date: 2024-01-02 17:10:06
Ethyl 7-(diethylamino)-2-oxo-2H-chromene-3-carboxylate is a potent and selective inhibitor of hMAO-B with an IC50 of 45.52 μM[1].

Name	ethyl 7-(diethylamino)-2-oxochromene-3-carboxylate
Synonyms	7-diethylamino-2-oxo-2H-1-benzopyran-3-carboxylic acid ethyl ester 7-(Diethylamino)coumarin-3-carboxylic Acid Ethyl Ester ethyl 7-diethylaminocoumarin-3-carboxylate Ethyl 7-(Diethylamino)coumarin-3-carboxylate 7-diethylamino-2-oxo-2H-chromene-3-carboxylic acid ethyl ester 7-diethylaminocoumarin-3-carboxylic acid ethyl ester ethyl 7-(diethylamino)-2-oxo-2H-[1]benzopyran-3-carboxylate ethyl 7-diethylamino-2-oxo-2H-chromene-3-carboxylate

Description	Ethyl 7-(diethylamino)-2-oxo-2H-chromene-3-carboxylate is a potent and selective inhibitor of hMAO-B with an IC50 of 45.52 μM[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> Monoamine Oxidase Research Areas >> Neurological Disease
References	[1]. Secci D, et al. Synthesis and selective human monoamine oxidase inhibition of 3-carbonyl, 3-acyl, and 3-carboxyhydrazido coumarin derivatives. Eur J Med Chem. 2011 Oct;46(10):4846-52.

HS Code	2932209090

17754-90-4

105-53-3

~87%

28705-46-6

Literature: Muller, Caroline; Even, Pascale; Viriot, Marie-Laure; Carre, Marie-Christiane Helvetica Chimica Acta, 2001 , vol. 84, # 12 p. 3735 - 3741

17754-90-4

105-56-6

~79%

28705-46-6

87-13-8

91-68-9

~33%

28705-46-6

Literature: Bissell Synthesis, 1982 , vol. No. 10, p. 846 - 848

Total: 1 Page

HS Code	2932209090
Summary	2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%