Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Phenylpiracetam
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Carphedon
Price: ￥100.0/250mg ￥170.0/1g
Purity: 98.0%
Stocking Period: 2 Day
Contact: Liu jia
Email: 2130147988@qq.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: Phenylpiracetam
Price: ￥Inquiry/1g
Purity: 98.9%
Stocking Period: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

DC Chemicals Limited
China
Product Name: Phenylpiracetam
Price: $700.0/100mg $1400.0/250mg $2800.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: 2-(2-Oxo-4-phenylpyrrolidin-1-yl)acetamide
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson
Email: info@tianfuchem.com

77472-70-9

77472-70-9 structure

Name: Carphedon
Chemical Name: 2-(2-Oxo-4-phenylpyrrolidin-1-yl)acetamide
CAS Number: 77472-70-9
Molecular Formula: C₁₂H₁₄N₂O₂
Molecular Weight: 218.252
Catalog: Organic raw materials Amino compound Oxy-containing amino compound
Create Date: 2018-07-15 14:16:52
Modify Date: 2025-08-27 10:11:36
Phenylpiracetam(Phenotropyl; Phenotropil) is a phenylated derivative of the nootropic drug piracetam. It is used as a stimulant nootropic drug that can be up to 30-60 times more potent than piracetam.IC50 Value:Target: AMPA receptor allosteric modulatorin vitro: N/Ain vivo: In the open-field test, a significant increase in locomotor activity was observed after a single administration of R-phenotropil at doses of 10 and 50 mg/kg and S-phenotropil at a dose of 50 mg/kg. In the forced swim test, R-phenotropil induced an antidepressant effect at doses of 100 and 50 mg/kg, and S-phenotropil was active at a dose of 100 mg/kg. R-phenotropil significantly enhanced memory function in a passive avoidance response test at a dose of 1 mg/kg; the S-enantiomer did not show any activity in this test [1].

Name	2-(2-Oxo-4-phenylpyrrolidin-1-yl)acetamide
Synonyms	fonturacetam UNII:99QW5JU66Y Carphedon Phenylpiracetam 4-Phenyl-2-pyrrolidone-1-acetamide 2-(2-Oxo-4-phenyl-1-pyrrolidinyl)acetamide 1-Pyrrolidineacetamide, 2-oxo-4-phenyl- 2-(2-oxo-4-phenylpyrrolidin-1-yl)acetamide 4-Phenylpiracetam Phenotropil

Description	Phenylpiracetam(Phenotropyl; Phenotropil) is a phenylated derivative of the nootropic drug piracetam. It is used as a stimulant nootropic drug that can be up to 30-60 times more potent than piracetam.IC50 Value:Target: AMPA receptor allosteric modulatorin vitro: N/Ain vivo: In the open-field test, a significant increase in locomotor activity was observed after a single administration of R-phenotropil at doses of 10 and 50 mg/kg and S-phenotropil at a dose of 50 mg/kg. In the forced swim test, R-phenotropil induced an antidepressant effect at doses of 100 and 50 mg/kg, and S-phenotropil was active at a dose of 100 mg/kg. R-phenotropil significantly enhanced memory function in a passive avoidance response test at a dose of 1 mg/kg; the S-enantiomer did not show any activity in this test [1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor Signaling Pathways >> Neuronal Signaling >> GABA Receptor Research Areas >> Neurological Disease
References	[1]. Zvejniece L, et al. Investigation into stereoselective pharmacological activity of phenotropil. Basic Clin Pharmacol Toxicol. 2011 Nov;109(5):407-12.

Density	1.2±0.1 g/cm3
Boiling Point	486.4±45.0 °C at 760 mmHg
Molecular Formula	C₁₂H₁₄N₂O₂
Molecular Weight	218.252
Flash Point	247.9±28.7 °C
Exact Mass	218.105530
PSA	64.39000
LogP	0.16
Vapour Pressure	0.0±1.2 mmHg at 25°C
Index of Refraction	1.580

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UX9663000

CHEMICAL NAME :: 1-Pyrrolidineacetamide, 2-oxo-4-phenyl-

CAS REGISTRY NUMBER :: 77472-70-9

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C12-H14-N2-O2

MOLECULAR WEIGHT :: 218.28

WISWESSER LINE NOTATION :: T5NVTJ A1VZ DR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1100 mg/kg

TOXIC EFFECTS :: Autonomic Nervous System - smooth muscle relaxant (mechanism undefined, spasmolytic) Behavioral - changes in motor activity (specific assay) Behavioral - muscle weakness

REFERENCE :: PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 14,776,1980

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: 1100 mg/kg

TOXIC EFFECTS :: Behavioral - changes in motor activity (specific assay) Behavioral - muscle weakness Behavioral - analgesia

REFERENCE :: RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 44,22,1981

HS Code	2933990090

70291-40-6

~99%

77472-70-9

Literature: Pharmaceutical Chemistry Journal, , vol. 14, # 11 p. 776 - 780 Khimiko-Farmatsevticheskii Zhurnal, , vol. 14, # 11 p. 43 - 48

68497-63-2

~81%

77472-70-9

Literature: J. Gen. Chem. USSR (Engl. Transl.), , vol. 58, # 5 p. 1093 - 1102,970 - 979

1198-97-6

77472-70-9

Literature: J. Gen. Chem. USSR (Engl. Transl.), , vol. 58, # 5 p. 1093 - 1102,970 - 979

106869-48-1

77472-70-9

Literature: J. Gen. Chem. USSR (Engl. Transl.), , vol. 58, # 5 p. 1093 - 1102,970 - 979

3060-41-1

77472-70-9

Literature: J. Gen. Chem. USSR (Engl. Transl.), , vol. 58, # 5 p. 1093 - 1102,970 - 979

77519-55-2

77472-70-9

Literature: Pharmaceutical Chemistry Journal, , vol. 14, # 11 p. 776 - 780 Khimiko-Farmatsevticheskii Zhurnal, , vol. 14, # 11 p. 43 - 48

55790-17-5

77472-70-9

Literature: Pharmaceutical Chemistry Journal, , vol. 14, # 11 p. 776 - 780 Khimiko-Farmatsevticheskii Zhurnal, , vol. 14, # 11 p. 43 - 48

Precursor 6
70291-40-6 68497-63-2 1198-97-6 3060-41-1
77519-55-2 55790-17-5
DownStream 0

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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