522664-63-7

522664-63-7 structure

Name: Ibodutant
Chemical Name: 6-methyl-N-[1-[[(2R)-1-[[1-(oxan-4-ylmethyl)piperidin-4-yl]methylamino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]cyclopentyl]-1-benzothiophene-2-carboxamide
CAS Number: 522664-63-7
Molecular Formula: C₃₇H₄₈N₄O₄S
Molecular Weight: 644.86600
Catalog: Signaling Pathways GPCR/G Protein Neurokinin Receptor
Create Date: 2017-03-08 05:57:46
Modify Date: 2024-01-31 23:10:45
MEN 15596 is a potent and selective tachykinin NK2 receptor antagonist with a pKi of 10.1.

Name	6-methyl-N-[1-[[(2R)-1-[[1-(oxan-4-ylmethyl)piperidin-4-yl]methylamino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]cyclopentyl]-1-benzothiophene-2-carboxamide
Synonyms	Ibodutant UNII-1H7RSQ28BJ

Description	MEN 15596 is a potent and selective tachykinin NK2 receptor antagonist with a pKi of 10.1.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Neurokinin Receptor Signaling Pathways >> Neuronal Signaling >> Neurokinin Receptor Research Areas >> Neurological Disease
Target	pKi: 10.1 (Tachykinin NK2 receptor)[1]
References	[1]. Cialdai C, et al. MEN15596, a novel nonpeptide tachykinin NK2 receptor antagonist. Eur J Pharmacol. 2006 Nov 7;549(1-3):140-8.