69956-77-0
69956-77-0 structure
- Name: Pelubiprofen
- Chemical Name: 2-[4-[(E)-(2-oxocyclohexylidene)methyl]phenyl]propanoic acid
- CAS Number: 69956-77-0
- Molecular Formula: C16H18O3
- Molecular Weight: 258.312
- Catalog: Signaling Pathways Immunology/Inflammation COX
- Create Date: 2018-06-18 19:26:21
- Modify Date: 2024-01-09 19:46:46
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Pelubiprofen, an orally active and non-steroidal anti-inflammatory drug, is a member of the 2-arylpropionic acid family and has relatively selective effects on COX-2 activity. Pelubiprofen inhibits COX activity and the transforming growth factor-β activated kinase 1-IκB kinase β-NF-κB pathway, and has significant anti-inflammatory and analgesic effects[1].
| Name | 2-[4-[(E)-(2-oxocyclohexylidene)methyl]phenyl]propanoic acid |
|---|---|
| Synonyms |
2-[4-(2-oxo-1-cyclohexyliden methyl)-phenyl]propionic acid
Benzeneacetic acid, α-methyl-4-[(E)-(2-oxocyclohexylidene)methyl]- 2-Ocmpp 2-{4-[(E)-(2-Oxocyclohexylidene)methyl]phenyl}propanoic acid (+/-)-2-[4-(2-Oxocyclohexylidenemethyl)phenyl]propionic acid (±)-p-[[(E)-2-Oxocyclohexylidene]methyl]hydratropic Acid Pelubiprofen Pelubiprofen (JAN/INN) 2-[4-(2-oxo-1-cyclohexylidenemethyl)phenyl]propionic acid MFCD00870907 |
| Description | Pelubiprofen, an orally active and non-steroidal anti-inflammatory drug, is a member of the 2-arylpropionic acid family and has relatively selective effects on COX-2 activity. Pelubiprofen inhibits COX activity and the transforming growth factor-β activated kinase 1-IκB kinase β-NF-κB pathway, and has significant anti-inflammatory and analgesic effects[1]. |
|---|---|
| Related Catalog | |
| Target |
COX-2 |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 457.4±34.0 °C at 760 mmHg |
| Molecular Formula | C16H18O3 |
| Molecular Weight | 258.312 |
| Flash Point | 244.5±22.2 °C |
| Exact Mass | 258.125580 |
| PSA | 54.37000 |
| LogP | 2.76 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.605 |
