103285-22-9

103285-22-9 structure

Name: 2'-O-Methyl-5'-O-DMT-Uridine;DMT-2'-OMe-U
Chemical Name: 1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-methoxyoxolan-2-yl]pyrimidine-2,4-dione
CAS Number: 103285-22-9
Molecular Formula: C₃₁H₃₂N₂O₈
Molecular Weight: 560.59
Catalog: Biochemical Nucleoside drugs Nucleoside intermediate
Create Date: 2018-12-01 10:39:50
Modify Date: 2024-01-09 06:58:52
5’-O-(4,4’-Dimethoxytrityl)-2’-O-methyluridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents[1].

Name	1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-methoxyoxolan-2-yl]pyrimidine-2,4-dione
Synonyms	DMT-2'-OMe-U 5'-O-DMT-2'-O-METHYL-URIDINE 5'-DMT 2'-O-methyl uridine 2'-O-methyl-5"-O-dimethoxytrityl uridine HG1364 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-uridine 2'-O-Methyl-5'-O-DMT-Uridine;DMT-2'-OMe-U

Description	5’-O-(4,4’-Dimethoxytrityl)-2’-O-methyluridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Connolly GP, et al. Uridine and its nucleotides: biological actions, therapeutic potentials. Trends Pharmacol Sci. 1999 May;20(5):218-25.

Molecular Formula	C₃₁H₃₂N₂O₈
Molecular Weight	560.59
Exact Mass	560.21600
PSA	121.24000
LogP	2.83580
Appearance	Powder \| White to Pale Yellow
Storage condition	Store dry at 2-8°C

109-88-6

173170-12-2

~65%

103285-22-9

Literature: Buettner, Lea; Seikowski, Jan; Wawrzyniak, Katarzyna; Ochmann, Anne; Hoebartner, Claudia Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 20 p. 6171 - 6180

40615-36-9

~99%

103285-22-9

Literature: ISIS Pharmaceuticals, Inc. Patent: US5914396 A1, 1999 ;

40615-36-9

2140-76-3

~90%

103285-22-9

Literature: Barbeyron, Renaud; Wengel, Jesper; Vasseur, Jean-Jacques; Smietana, Michael Monatshefte fur Chemie, 2013 , vol. 144, # 4 p. 495 - 500

3736-77-4

103285-22-9

Literature: Bioorganic and Medicinal Chemistry, , vol. 21, # 20 p. 6171 - 6180

58-96-8

103285-22-9

Literature: Bioorganic and Medicinal Chemistry, , vol. 21, # 20 p. 6171 - 6180

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