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103285-22-9

103285-22-9 structure
103285-22-9 structure
  • Name: 2'-O-Methyl-5'-O-DMT-Uridine;DMT-2'-OMe-U
  • Chemical Name: 1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-methoxyoxolan-2-yl]pyrimidine-2,4-dione
  • CAS Number: 103285-22-9
  • Molecular Formula: C31H32N2O8
  • Molecular Weight: 560.59
  • Catalog: Biochemical Nucleoside drugs Nucleoside intermediate
  • Create Date: 2018-12-01 10:39:50
  • Modify Date: 2026-07-01 08:13:36
  • 5’-O-(4,4’-Dimethoxytrityl)-2’-O-methyluridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents[1].

Name 1-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-methoxyoxolan-2-yl]pyrimidine-2,4-dione
Synonyms oligoadenylate Synthetase 1, 40/46kD, IFI-4, OIAS, OIASI) (Biotin)
HG1364
5'-O-DMT-2'-O-METHYL-URIDINE
cyclic Phosphodiesterase B, Cyclic GMP-inhibited Phosphodiesterase B, HcGIP1)
nucleotidase, Thiamine Monophosphatase, TMPase) (PE)
5'-DMT 2'-O-methyl uridine
cyclic Monophosphate) (HPLC)
cyclic phosphodiesterase 4C, PDE21)
deoxyinosine (HPLC)
Dibromoacetophenone &ge
P1,P3-triphosphate hydrolase, Dinucleosidetriphosphatase, Tumor Suppressor Protein, AP3Aase, FRA3B)
nucleotidase 1, PAP-inositol 1,4-phosphatase, PIP)
5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-methyl-uridine
8-d3
dimethoxytrityl) thymidine (synthetic) (TLC)
cyclic phosphodiesterase 4B, DPDE4, PDE32) (APC)
cyclic phosphodiesterase 8B, Cell proliferation-inducing gene 22 protein)
NT, eN, eNT, NT5, NT5E, NTE, Purine 5 Prime Nucleotidase)
Cyclic-AMP and -GMP Phosphodiesterase 11A, cAMP and cGMP Phosphodiesterase 11A)
5'-O-(DIMETHOXYTRITYL)-2'-O-METHYLURIDINE
trifluoroacetamidocytidine
cyclic nucleotide phosphodiesterase 1B, PDE1B1, PDES1B)
P1,P6-hexaphosphate Hydrolase 1, Nucleoside Diphosphate-linked Moiety X Motif 3, Nudix Motif 3, DIPP, DIPP1)
5'-O-(4,4'-DIMETHOXYTRITYL)-2'-O-METHYLURIDINE
DMT-2'-OMe-U
DMT-2'-O-METHYLURIDINE
anhydrouridine
cyclic Phosphodiesterase Subunit Alpha, Phosphodiesterase 6C, cGMP-specific, Cone, Alpha Prime)
2'-O-methyl-5"-O-dimethoxytrityl uridine
Nucleotidase, Cytosolic III (NT5C3)
PDE10A, BioAssay&trade
1-((2R,3R,4R,5R)-5-((bis(4-Methoxyphenyl)(phenyl)Methoxy)Methyl)-4-hydroxy-3-Methoxytetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione
oligoadenylate Synthase-like Protein, p59 OASL, p59OASL, Thyroid Rector-interacting Protein 14, TR-interacting Protein 14, TRIP-14, TRIP14)
pyrophosphohydrolase, (ppGpp)ase, MESH1)
cyclic Phosphodiesterase 9A, FLJ90181, HSPDE9A2)
PDE3B, BioAssay&trade
5'-O-DMT-2'-O-methyluridine
Exonuclease TREX1, AGS1, CRV, DNase III, DRN3, HERNS)
bisphosphate, Triethylammonium Salt (Biotin)
cyclic phosphodiesterase subunit delta, Protein p17)
P1,P4-tetraphosphate asymmetrical hydrolase, Nucleoside diphosphate-linked moiety X motif 2)
cyclic Phosphodiesterase B, CGIPDE1, CGIP1, Cyclic GMP-inhibited Phosphodiesterase B, CGI-PDE B)
Methoxylaudanosine
dimethoxybenzyloxy)phenylboronic acid
Uridine, 5'-O-[bis(4-Methoxyphenyl)phenylMethyl]-2'-O-Methyl
5'-O-DMT-2'-O-methyl-D-uridine
deoxy-b-D-ribofuranosyl]guanine
terthiophene]-5-cbaldehyde
cyclic Phosphodiesterase 10A)
nucleotidase 1, PIP, PAP-inositol-1,4-phosphatase, HEL20)
bisphosphate nucleotidase 1, PIP)
nucleotidase 1, PAP-inositol 1,4-phosphatase)
Bis-(S)-phosphate
cyclic Nucleotide Phosphodiesterase 1A, Cam-PDE 1A, 61kD Cam-PDE, hCam-1, M26303) (FITC)
cyclic Phosphodiesterase A, Cyclic GMP-inhibited Phosphodiesterase A, CGI-PDE A) (FITC)
deoxyadenosine &ge
tri-O-tert-butyldimethylsilyl-b-D-ribofuranosyl)-imidazo[4,5-c]pyridine
oligoadenylate synthase 1, E18/E16, p46/p42 OAS)
d4 3-O-&beta
cyclic phosphodiesterase 4C, PDE21) (PE)
cyclic Phosphodiesterase 10A, FLJ11894, FLJ25677, HSPDE10A) (PE)
)oligo(A) Synthase 3, A Synthase 3, p100 OAS, p100OAS, P/OKcl.4) (FITC)
di-O-tritylguanosine
Description 5’-O-(4,4’-Dimethoxytrityl)-2’-O-methyluridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents[1].
Related Catalog
References

[1]. Connolly GP, et al. Uridine and its nucleotides: biological actions, therapeutic potentials. Trends Pharmacol Sci. 1999 May;20(5):218-25.  

Molecular Formula C31H32N2O8
Molecular Weight 560.59
Exact Mass 560.21600
PSA 121.24000
LogP 2.83580
Appearance Powder | White to Pale Yellow
Storage condition Store dry at 2-8°C

~65%

103285-22-9 structure

103285-22-9

Literature: Buettner, Lea; Seikowski, Jan; Wawrzyniak, Katarzyna; Ochmann, Anne; Hoebartner, Claudia Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 20 p. 6171 - 6180

~99%

103285-22-9 structure

103285-22-9

Literature: ISIS Pharmaceuticals, Inc. Patent: US5914396 A1, 1999 ;

~90%

103285-22-9 structure

103285-22-9

Literature: Barbeyron, Renaud; Wengel, Jesper; Vasseur, Jean-Jacques; Smietana, Michael Monatshefte fur Chemie, 2013 , vol. 144, # 4 p. 495 - 500

~%

103285-22-9 structure

103285-22-9

Literature: Bioorganic and Medicinal Chemistry, , vol. 21, # 20 p. 6171 - 6180

~%

103285-22-9 structure

103285-22-9

Literature: Bioorganic and Medicinal Chemistry, , vol. 21, # 20 p. 6171 - 6180
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