63233-46-5

63233-46-5 structure
63233-46-5 structure
  • Name: KW-6055
  • Chemical Name: N-[3-nitro-4-(pyridin-2-ylmethyl)phenyl]butanamide
  • CAS Number: 63233-46-5
  • Molecular Formula: C16H17N3O3
  • Molecular Weight: 299.32400
  • Catalog: Research Areas Neurological Disease
  • Create Date: 2016-01-10 14:42:49
  • Modify Date: 2024-01-09 20:30:22
  • KW-6055 is a benzylpyridine derivative and has anti-amnesic activity.

Name N-[3-nitro-4-(pyridin-2-ylmethyl)phenyl]butanamide
Synonyms N-(3-Nitro-4-(2-pyridinylmethyl)phenyl)butanamide
2-(4-Butyrylamino-2-nitrobenzyl)pyridine
KW 6055
Butanamide,N-(3-nitro-4-(2-pyridinylmethyl)phenyl)
KW-6055
Description KW-6055 is a benzylpyridine derivative and has anti-amnesic activity.
Related Catalog
In Vivo KW-6055 is a benzylpyridine derivative and has anti-amnesic activity. KW-6055 (40, 160 mg/kg, p.o.) increases the extracellular level of ACh in normal rats (257±23, 202±24%). In basal forebrain-lesioned rats, KW-6055 (40 mg/kg, p.o.) significantly increases the extracellular level of ACh (251±22%) for more than 2 hr, which is longer than in normal rats[1].
References

[1]. Kurokawa M, et al. Effects of KW-6055, a novel benzylpyridine derivative, on central cholinergic systems. Nihon Yakurigaku Zasshi. 1992 Jun;99(6):435-43.

Density 1.247g/cm3
Boiling Point 492.6ºC at 760mmHg
Molecular Formula C16H17N3O3
Molecular Weight 299.32400
Flash Point 251.7ºC
Exact Mass 299.12700
PSA 91.30000
LogP 4.49190
Storage condition 2-8℃