86137-72-6
86137-72-6 structure
- Name: 2'-Deoxy-6-O-[2-(4-nitrophenyl)ethyl]guanosine
- Chemical Name: 2'-deoxy-O6-[2-(4-nitrophenyl)ethyl]guanosine
- CAS Number: 86137-72-6
- Molecular Formula: C18H20N6O6
- Molecular Weight: 416.39
- Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
- Create Date: 2016-09-12 15:11:57
- Modify Date: 2024-01-14 11:41:46
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2’-Deoxy-O6-[2-(4-nitrophenylethyl)]guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
| Name | 2'-deoxy-O6-[2-(4-nitrophenyl)ethyl]guanosine |
|---|---|
| Synonyms |
2'-DEOXY-6-O-[2-(4-NITROPHENYL)ETHYL]GUANOSINE
6-O-(4-nitrophenylethyl)-2''-deoxyguanosine O-6-(p-nitrophenylethyl)-2''-deoxyguanosine 2''-deoxy-O6-[2-(4-nitrophenyl)ethyl]guanosine 6-O-(tert-Butyldiphenylsilyl)-3,4-O-isopropylidene-D-galactal |
| Description | 2’-Deoxy-O6-[2-(4-nitrophenylethyl)]guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C18H20N6O6 |
|---|---|
| Molecular Weight | 416.39 |
| Exact Mass | 416.14400 |
| PSA | 174.36000 |
| LogP | 1.68330 |
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~%
86137-72-6 |
| Literature: He; Krawczyk; Swaminathan; Shea; Dougherty; Terhorst; Law; Griffin; Coutre; Bischofberger Journal of medicinal chemistry, 1998 , vol. 41, # 13 p. 2234 - 2242 |
| Precursor 1 | |
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| DownStream 2 | |
