GL Biochem (Shanghai) Ltd.
China
Product Name: Tetracosactide Acetate
Price: $Inquiry/1kg
Purity: 98.0%
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Contact: Jackie Yang

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Cosyntropin
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
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Zhejiang Hangyu API Co., Ltd
China
Product Name: Cosyntropin
Price: ￥Inquiry/1kg
Purity: 99.5%
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Contact: Vinnie

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Tetracosactide Injection
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

16960-16-0

16960-16-0 structure

Name: Adrenocorticotropic Hormone Fragment 1-24 human
Chemical Name: Cosyntropin
CAS Number: 16960-16-0
Molecular Formula: C₁₃₆H₂₁₀N₄₀O₃₁S
Molecular Weight: 2933.437
Catalog: API Hormone and endocrine-regulating drugs Adrenocorticotropic drugs
Create Date: 2018-06-12 10:41:53
Modify Date: 2024-01-02 15:52:26
Tetracosactide (INN) is an analogue of adrenocorticotrophic hormone (ACTH), with the biological activity of stimulating production of corticosteroids in the adrenal cortex. Sequence: Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro.

Name	Cosyntropin
Synonyms	Cortrosyn y-29-(4-hydroxybenzyl)-26-(hydroxymethyl)-17-(1H-imidazol-4-ylmethyl)-8-(1H-indol-3-ylmethyl)-23-[2-(methylsulfanyl)ethyl]-4,7,10,13,16,19,22,25,28,31-decaoxo-3,6,9,12,15,18,21,24,27,30-decaazatritria L-proline, L-seryl-L-tyrosyl-L-seryl-L-methionyl-L-α-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl-L-lysyl-L-prolyl-L-valylglycyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-prolyl-L-valyl-L-lysyl-L-valyl-L-tyrosyl- MFCD00167476 L-Proline, L-seryl-L-tyrosyl-L-seryl-L-methionyl-L-α-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl-L-lysyl-L-prolyl-L-valylglycyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-prolyl-L-v alyl-L-lysyl-L-valyl-L-tyrosyl- cosyntropin α1-24-Corticotropin L-Seryl-L-tyrosyl-L-seryl-L-methionyl-L-α-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl-L-lysyl-L-prolyl-L-valylglycyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-prolyl-L-valyl-L-lysyl-L-valyl-L-tyrosyl-L-proline EINECS 241-031-1 Adrenocorticotropic Hormone Fragment 1-24 human, rat Tetracosactide L-seryl-L-tyrosyl-L-seryl-L-methionyl-L-α-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl-L-lysyl-L-prolyl-L-valylglycyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-prolyl-L-valyl-L-lysy L-Seryl-L-tyrosyl-L-seryl-L-methionyl-L-α-glutamyl-L-histidyl-L-phenylalanyl-L-arginyl-L-tryptophylglycyl-L-lysyl-L-prolyl-L-valylglycyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-prolyl-L-valyl-L-lysy l-L-valyl-L-tyrosyl-L-proline Porcine ACTH (1-24) Tetracosactide Acetate

Description	Tetracosactide (INN) is an analogue of adrenocorticotrophic hormone (ACTH), with the biological activity of stimulating production of corticosteroids in the adrenal cortex. Sequence: Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Cancer Peptides

Density	1.5±0.1 g/cm3
Molecular Formula	C₁₃₆H₂₁₀N₄₀O₃₁S
Molecular Weight	2933.437
Exact Mass	2931.580566
PSA	1184.02000
LogP	-3.27
Index of Refraction	1.681
Storage condition	−20°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GM7915000

CHEMICAL NAME :: alpha(sup 1-24)-Corticotropin

CAS REGISTRY NUMBER :: 16960-16-0

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C136-H210-N40-O31-S

MOLECULAR WEIGHT :: 2933.92

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Human - woman

DOSE/DURATION :: 5 ug/kg

TOXIC EFFECTS :: Cardiac - change in rate Lungs, Thorax, or Respiration - cyanosis Lungs, Thorax, or Respiration - other changes

REFERENCE :: JAMAAP JAMA, Journal of the American Medical Association. (AMA, 535 N. Dearborn St., Chicago, IL 60610) V.1- 1883- Volume(issue)/page/year: 237,879,1977 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4549 No. of Facilities: 24 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 1071 (estimated) No. of Female Employees: 546 (estimated)

RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	GM7915000

16960-16-0	97773-00-7
2791-05-1	7266-47-9
5576-42-1	26469-81-8
1926163-11-2	1815617-95-8
494750-52-6	148943-65-1