130714-47-5

130714-47-5 structure

Name: SDZ WAG 994
Chemical Name: SDZ WAG 994,N-Cyclohexyl-2'-O-methyladenosine
CAS Number: 130714-47-5
Molecular Formula: C₁₇H₂₅N₅O₄
Molecular Weight: 363.41
Catalog: Signaling Pathways GPCR/G Protein Adenosine Receptor
Create Date: 2017-02-12 21:45:32
Modify Date: 2024-01-12 17:15:48
SDZ-WAG994 (WAG-994) is a stable, long-acting, selective and orally active A1-adenosine receptor agonist with a KD of 23 nM. SDZ-WAG994 can be used for the research of atrial fibrillation[1].

Name	SDZ WAG 994,N-Cyclohexyl-2'-O-methyladenosine
Synonyms	N-Cyclohexyl-2'-O-methyladenosine SDZWAG994

Description	SDZ-WAG994 (WAG-994) is a stable, long-acting, selective and orally active A1-adenosine receptor agonist with a KD of 23 nM. SDZ-WAG994 can be used for the research of atrial fibrillation[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> GPCR/G Protein >> Adenosine Receptor
Target	KD: 23 nM (A1-adenosine receptor)[1]
References	[1]. O Piot, et al. Effects of a selective A1-adenosine receptor agonist on heart rate and heart rate variability during permanent atrial fibrillation. Pacing Clin Electrophysiol. 1998 Nov;21(11 Pt 2):2459-64. [2]. Wagner H, et al. General pharmacology of SDZ WAG 994, a potent selective and orally active adenosine A1 receptor agonist. Drug development research, 1995, 34(3): 276-288. [3]. Piot O, et al. Effects of a selective A1-adenosine receptor agonist on heart rate and heart rate variability during permanent atrial fibrillation. Pacing Clin Electrophysiol. 1998 Nov;21(11 Pt 2):2459-64.