Top Suppliers:I want be here


  • DC Chemicals Limited
  • China
  • Product Name: NE-100
  • Price: $400.0/100mg $700.0/250mg $1350.0/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

149409-57-4

149409-57-4 structure
149409-57-4 structure
  • Name: NE 100 hydrochloride
  • Chemical Name: N,N-diethyl-2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethanamine,hydrochloride
  • CAS Number: 149409-57-4
  • Molecular Formula: C23H34ClNO2
  • Molecular Weight: 391.97500
  • Create Date: 2018-06-21 21:43:01
  • Modify Date: 2024-02-03 15:04:15
  • NE-100 (hydrochloride) is a potent and selective sigma-1 receptor antagonist with an IC50 of 4.16 nM. NE-100 (hydrochloride) exerts antipsychotic activity in vivo[1]. NE-100 (hydrochloride) also suppresses ER stress-induced hippocampal cell death[2].

Name N,N-diethyl-2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethanamine,hydrochloride
Synonyms ne 100
NE-100
Description NE-100 (hydrochloride) is a potent and selective sigma-1 receptor antagonist with an IC50 of 4.16 nM. NE-100 (hydrochloride) exerts antipsychotic activity in vivo[1]. NE-100 (hydrochloride) also suppresses ER stress-induced hippocampal cell death[2].
Related Catalog
References

[1]. Okuyama S, et al. NE-100, a novel sigma receptor ligand: in vivo tests. Life Sci. 1993;53(18):PL285-90.

[2]. Ono Y, et al. A sigma-1 receptor antagonist (NE-100) prevents tunicamycin-induced cell death via GRP78 induction in hippocampal cells. Biochem Biophys Res Commun. 2013 May 17;434(4):904-9.

Boiling Point 475.2ºC at 760 mmHg
Molecular Formula C23H34ClNO2
Molecular Weight 391.97500
Flash Point 137.4ºC
Exact Mass 391.22800
PSA 21.70000
LogP 5.78320
Vapour Pressure 3.37E-09mmHg at 25°C
RIDADR NONH for all modes of transport