202468-25-5

202468-25-5 structure

Name: L-Arginine-13C6,15N4 hydrochloride
Chemical Name: L-Arginine:Hcl (13C,15N4)
CAS Number: 202468-25-5
Molecular Formula: ₁₃C₆H₁₅Cl₁₅N₄O₂
Molecular Weight: 220.592
Catalog: Signaling Pathways Immunology/Inflammation NO Synthase
Create Date: 2017-08-29 01:23:37
Modify Date: 2024-01-09 16:09:27
L-Arginine-13C6,15N4 ((S)-(+)-Arginine-13C6,15N4) hydrochloride is the 13C- and 15N-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.

Name	L-Arginine:Hcl (13C,15N4)
Synonyms	L-(C,N)Arginine hydrochloride (1:1) L-Arginine-C-N, hydrochloride (1:1)

Description	L-Arginine-13C6,15N4 ((S)-(+)-Arginine-13C6,15N4) hydrochloride is the 13C- and 15N-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.
Related Catalog	Research Areas >> Others Signaling Pathways >> Immunology/Inflammation >> NO Synthase
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.