204244-77-9

204244-77-9 structure

Name: L-Arginine-d7 hydrochloride
Chemical Name: L-Arginine:Hcl (D7)
CAS Number: 204244-77-9
Molecular Formula: C₆H₈D₇ClN₄O₂
Molecular Weight: 217.705
Catalog: Signaling Pathways Immunology/Inflammation NO Synthase
Create Date: 2016-12-14 21:56:44
Modify Date: 2024-01-09 08:38:16
L-Arginine-d7 ((S)-(+)-Arginine-d7) hydrochloride is the deuterium labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.

Name	L-Arginine:Hcl (D7)
Synonyms	L-(2,3,3,4,4,5,5-2H7)Arginine hydrochloride (1:1) MFCD00144556 L-Arginine-2,3,3,4,4,5,5-d7, hydrochloride (1:1)

Description	L-Arginine-d7 ((S)-(+)-Arginine-d7) hydrochloride is the deuterium labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.
Related Catalog	Research Areas >> Others Signaling Pathways >> Immunology/Inflammation >> NO Synthase
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.