1204085-48-2

1204085-48-2 structure

Name: Biotin-PEG1-azide
Chemical Name: N-[2-(2-Azidoethoxy)ethyl]-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide
CAS Number: 1204085-48-2
Molecular Formula: C₁₄H₂₄N₆O₃S
Molecular Weight: 356.44400
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
Create Date: 2018-12-02 15:58:42
Modify Date: 2024-01-17 07:50:54
Biotin-PEG1-azide is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name	N-[2-(2-Azidoethoxy)ethyl]-5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamide

Description	Biotin-PEG1-azide is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Target	Cleavable
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References	[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.