4168-17-6

4168-17-6 structure

Name: Catharanthine Tartrate
Chemical Name: Bis[(5ξ,18ξ)-18-(methoxycarbonyl)-3,4-didehydroibogamin-6-ium] tartarate
CAS Number: 4168-17-6
Molecular Formula: C₄₆H₅₄N₄O₁₀
Molecular Weight: 822.942
Catalog: Signaling Pathways Membrane Transporter/Ion Channel Calcium Channel
Create Date: 2018-07-24 09:42:55
Modify Date: 2024-01-03 17:20:37
Catharanthine Tartrate is an alkaloid isolated from Madagascar periwinkle, inhibits voltage-operated L-type Ca2+ channel, with anti-cancer and blood pressure-lowering activity[1].

Name	Bis[(5ξ,18ξ)-18-(methoxycarbonyl)-3,4-didehydroibogamin-6-ium] tartarate
Synonyms	Ibogamine-18-carboxylic acid, 3,4-didehydro-, methyl ester, (5ξ,18ξ)-, 2,3-dihydroxybutanedioate (2:1) (salt) (2R,3R)-2,3-Dihydroxysuccinic acid - methyl (2α,5β,18β)-3,4-didehydroibogamine-18-carboxylate (1:2) Bis[(5ξ,18ξ)-18-(methoxycarbonyl)-3,4-didehydroibogamin-6-ium] tartarate

Description	Catharanthine Tartrate is an alkaloid isolated from Madagascar periwinkle, inhibits voltage-operated L-type Ca2+ channel, with anti-cancer and blood pressure-lowering activity[1].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Calcium Channel Research Areas >> Cancer Research Areas >> Cardiovascular Disease
References	[1]. Jadhav A, et al. Catharanthine dilates small mesenteric arteries and decreases heart rate and cardiac contractility by inhibition of voltage-operated calcium channels on vascular smooth muscle cells and cardiomyocytes. J Pharmacol Exp Ther. 2013 Jun;345(3):383-92.