89211-34-7

89211-34-7 structure

Name: Hydroxy-PEG1-acid
Chemical Name: 3-(2-hydroxyethoxy)propionic acid
CAS Number: 89211-34-7
Molecular Formula: C₅H₁₀O₄
Molecular Weight: 134.13000
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
Create Date: 2018-12-28 12:33:33
Modify Date: 2024-01-14 18:13:28
Hydroxy-PEG1-acid is a non-cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name	3-(2-hydroxyethoxy)propionic acid
Synonyms	3-(2-Hydroxy-ethoxy)-propionsaeure

Description	Hydroxy-PEG1-acid is a non-cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Target	Non-cleavable
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
References	[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.