Shanghai Nianxing Industrial Co., Ltd
China
Product Name: α-MaleiMidopropionyl-ω-succiniMidyl-8(ethyleneglycol)
Price: Check
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Chengdu Pukang Biotechnology Co., Ltd.
China
Product Name: Maleimide-PEG8-NHS Ester
Price: ￥Inquiry/10kg
Purity: 95.0%
Stocking Period: Inquiry
Contact: Lihua Yang
Email: sales@pu-kang.com

DC Chemicals Limited
China
Product Name: Mal-amido-PEG8-NHS
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

756525-93-6

756525-93-6 structure

756525-93-6 structure

Name: Mal-amido-PEG8-NHS ester
Chemical Name: Mal-PEG8-NHS
CAS Number: 756525-93-6
Molecular Formula: C₃₀H₄₇N₃O₁₅
Molecular Weight: 689.70500
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-01-04 20:03:24
Modify Date: 2024-04-05 11:45:56
Mal-amido-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	Mal-PEG8-NHS
Synonyms	α-Maleimidopropionyl-ω-succinimidyl-8(ethylene glycol) succinimidyl[(N-maleimidopropionamido)octaethyleneglycol]ester Alpha-Maleimidopropionyl-ω-succinimidyl-8(ethylene glycol) [3-[2-[2-[2-[2-[2-[2-[2-[3-(2,5-dioxo-2,5-dihydro-pyrrol-1-yl)-propionylamino]-ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]-propionic acid-2,5-dioxo-pyrrolidin-1-yl ester Maleimide-PEG8-NHS Ester

Description	Mal-amido-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula	C₃₀H₄₇N₃O₁₅
Molecular Weight	689.70500
Exact Mass	689.30100
PSA	204.00000
Storage condition	2-8°C

RIDADR	NONH for all modes of transport

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