1353016-70-2

1353016-70-2 structure

Name: DBCO-acid
Chemical Name: 4-(11,12-didehydrodibenzo[b,f]azocin-5(6H)-yl)-4-oxobutanoic acid
CAS Number: 1353016-70-2
Molecular Formula: C₁₉H₁₅NO₃
Molecular Weight: 305.32700
Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
Create Date: 2018-02-26 05:18:22
Modify Date: 2024-01-03 12:42:51
DBCO-acid is a cleavable ADC linker used in the synthesis of ADC linker DBCO-NHS ester (HY-115524 and HY-115545), and drug-linker conjugates DBCO-PEG-MMAE (HY-111012 and HY-126690)[1].

Name	4-(11,12-didehydrodibenzo[b,f]azocin-5(6H)-yl)-4-oxobutanoic acid
Synonyms	DBCO acid 1

Description	DBCO-acid is a cleavable ADC linker used in the synthesis of ADC linker DBCO-NHS ester (HY-115524 and HY-115545), and drug-linker conjugates DBCO-PEG-MMAE (HY-111012 and HY-126690)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Target	Cleavable
References	[1]. Zimmerman ES, et al. Production of site-specific antibody-drug conjugates using optimized non-natural amino acids in a cell-free expression system. Bioconjug Chem. 2014 Feb 19;25(2):351-61.